Immunoglobulin A deficiency(IgAD)
Also known as: IgA Deficiency · Selective IgA Deficiency · Immunglobulin-A-Mangel · Selective Immunoglobulin A Deficiency · Selektiver IgA-Mangel · …
Overview
What it is
Immunoglobulin A (IgA) deficiency is an immune system disorder where the body does not produce enough IgA, which is a key antibody that protects mucosal surfaces. This weakens the local defense system of the respiratory and gastrointestinal tracts, making the dog more vulnerable to infections and chronic inflammation in these areas.
How it presents
Owners typically notice symptoms during puppyhood or adolescence, which commonly include recurrent respiratory infections, chronic diarrhea, or persistent skin issues. Some dogs with this deficiency may remain completely healthy and show no symptoms at all.
Treatment
While there is no cure, the condition is manageable with lifelong symptomatic care, including targeted antibiotics, specialized diets, and skin treatments. Managing these chronic secondary issues typically costs between 1,500 and 6,000 EUR over the dog's lifetime.
How it's tested
Serum-IgA-Bestimmung(IgA-Messung)
Primary testClinical examBestimmung der Immunglobulin-A-Konzentration im Blutserum mittels ELISA oder radialer Immundiffusion (RID) zur Diagnose eines IgA-Mangels.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Immunoglobulin A deficiency?
Immunoglobulin A (IgA) deficiency is an immune system disorder where the body does not produce enough IgA, which is a key antibody that protects mucosal surfaces. This weakens the local defense system of the respiratory and gastrointestinal tracts, making the dog more vulnerable to infections and chronic inflammation in these areas.
How is Immunoglobulin A deficiency tested?
Tests currently in our database: Serum-IgA-Bestimmung.
Which breeds are most affected?
Most commonly affected: Beagle, German Shepherd, Shar-Pei, West Highland White Terrier.