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Health Testing Guide
Which tests are mandatory, how to spot responsible breeders — and what it costs when things go wrong.
For the Shar-Pei we have compiled 7 mandatory and 11 recommended health tests, drawn from breed-club regulations, the University of PEI (CIDD), and OMIA — weighted by severity and heritability.
What this grade means
The Shar Pei faces an above-average number of health challenges, which is reflected in the 8 mandatory health tests required for the breed. Breed-specific skin conditions, such as generalized demodicosis, as well as joint issues like hip dysplasia (HD), place a significant burden on the breed. Furthermore, unpredictable epilepsy poses a serious risk, which is why prospective puppy buyers must be extremely careful when selecting a breeder.
Every breed is susceptible to certain inherited conditions. Just like humans, dogs inherit predispositions from their parents. Responsible breeders screen their breeding dogs for these conditions and make informed mating decisions to reduce the risk passed on to puppies.
No — but it's the strongest tool we have. Diet, exercise, environment, and genetics all contribute to whether a dog develops a condition. When breeders use the right tests to identify risk in potential parents, the likelihood of many conditions appearing in the puppies drops significantly.
There's no one-size-fits-all here. For the Shar-Pei we track 7 mandatory tests plus 11 additional recommended ones. The specific tests and passing thresholds are detailed further below.
Keep in mind
Reliable screening tests still don't exist for many hereditary conditions, and tests for complex polygenic conditions are not always predictive of severity in the puppies. Even so, they're a powerful tool used by every responsible breeder.
There are two main types of health tests:
Screen the dog's DNA for known disease-causing mutations. Can be performed from puppyhood and give a binary result (clear / carrier / affected).
Clinical and imaging exams like X-ray, ultrasound, or ophthalmoscopy. They show how a predisposition actually manifests — usually only conclusive after 12–18 months.
We group breeding programs into three levels based on testing depth. Ask your breeder directly which level they meet.
A breeder at the Great level performs all mandatory tests plus 11 additional clinically recommended screenings that reduce risk in this breed.
In addition to mandatory tests:
Cleft palate
Allgemeine Fitness und Anatomie
A cleft palate is a congenital birth defect where the roof of the mouth fails to fuse properly during development in the womb. This failure leaves an abnormal opening between the oral cavity and the nasal passages. Because these two systems are directly connected, food, liquids, and air cannot be properly separated during swallowing.
Physisch · Passing: CLEAR
Brachycephalic obstructive airway syndrome (BOAS)(BOAS)
Atmung
Brachycephalic obstructive airway syndrome (BOAS) is a severe respiratory condition affecting short-muzzled dog breeds, where the physical shortening of the skull leaves insufficient space for the upper airways. This structural compression forces tissues like the soft palate and nasal passages into a restricted area, significantly obstructing the flow of oxygen to the lungs. Over time, the increased effort required to breathe puts chronic strain on the dog's respiratory and cardiovascular systems.
Physisch
Cataract(HC)
Augen und Sehvermögen
A cataract is a progressive clouding of the lens inside the dog's eye, which is the clear structure that focuses light onto the retina at the back of the eye. When the lens becomes cloudy or opaque, it blocks light from entering, gradually impairing the dog's vision. If left untreated, this condition can eventually lead to complete blindness in the affected eye.
Augen
Lens luxation(PLL)
Augen und Sehvermögen
Lens luxation is an inherited eye disorder where the lens slips out of its normal position because the supporting fibers holding it in place weaken or break. When the lens shifts, it can block the natural drainage of fluid within the eye. This blockage causes a rapid, painful buildup of pressure called glaucoma, which can lead to permanent blindness if left untreated.
Augen
Patellar Luxation(PL)
Bewegungsapparat
Patellar luxation, also known as a luxating patella, is a physical condition affecting the knee joint where the kneecap slips out of its normal groove. This misalignment interferes with the mechanical movement of the hind leg and can cause the joint to lock. Over time, this abnormal friction can lead to painful joint wear and tear, known as osteoarthritis.
Physisch · Passing: 0
Atopy(CAD)
Haut und Fell
Atopy is a chronic allergic skin disease where a dog's immune system overreacts to common environmental substances like pollen, mold spores, and dust mites. This inappropriate immune response damages the natural protective barrier of the skin, leading to persistent inflammation and irritation. It primarily affects the skin, which is the body's largest organ system.
Haut
Demodicosis / Demodectic mange
Haut und Fell
Demodicosis is a skin disease caused by an overgrowth of microscopic Demodex mites that naturally live inside a dog's hair follicles. While these mites are normally harmless, an inherited or acquired weakness in the immune system can allow them to multiply uncontrollably. This overgrowth leads to inflammation and damage to the skin barrier.
Haut
Epilepsy(IE)
Nervensystem
Epilepsy is a chronic disorder of the brain and nervous system where abnormal electrical activity causes sudden, temporary disruptions in normal brain function. These disruptions lead to repeated seizures, which are involuntary changes in body movement, sensation, or behavior. Because the underlying cause is often complex, the brain's electrical signaling remains permanently prone to these sudden misfires.
Physisch · Passing: General breeding exclusion
Familial Nephropathy(JEB)
Nieren und Harnwege
Familial Nephropathy (FN) is an inherited kidney disease caused by a genetic defect in collagen, which is a vital structural protein. This defect damages the kidneys' filtering units, preventing them from properly removing waste products from the blood. Over time, this leads to progressive and irreversible kidney failure.
Koerperfluessigkeiten
Megaesophagus(ME)
Verdauung und Darm
Megaesophagus is a disorder of the digestive system where the esophagus, the muscular tube connecting the throat to the stomach, becomes abnormally stretched and loses its muscle tone. Because these muscles can no longer contract to push food and liquid downward, meals become trapped in the tube. This trapped material is typically regurgitated, meaning it is passively cast back up before ever reaching the stomach.
Roentgen
Progressive Retinal Atrophy (prcd-PRA)(PRA)
Progressive rod-cone degeneration (prcd-PRA) is an inherited eye disease that causes the light-sensitive cells in the retina, which lines the back of the eye, to gradually break down and die. This degeneration affects both eyes and eventually leads to complete blindness. Because the retina cannot process light properly, the dog's brain stops receiving visual information.
Passing: CARRIER
These levels are a comparison framework, not an official certification. They help compare breeding programs at a glance.
A complete checklist with every mandatory and recommended test plus identity and rearing questions — take it with you.
Open the full checklistFor breeders
Machine-readable mating rules, minimum ages, scoring schemes, and what's required for HonestDog verification — as a printable guide.
Example rule — Hip dysplasia
Both parents must be C or better (HD-C must be bred to HD-A) or better.
We compile mandatory tests from official breed regulations and veterinary databases — and check every uploaded certificate for authenticity.
L1 = mandatory under breed-club regulations. L2 = recommended or clinically indicated. L3 = lower prevalence. Every assignment carries a source and confidence rating.
VDH breeding regulations, CIDD (University of PEI), OMIA (University of Sydney), curated veterinary input.
Uploaded certificates are AI-extracted and reviewed by our team for authenticity, date, and result.
7 tests are currently mandatory under the relevant breed-club regulations. The most common are DNA-Identitätsnachweis, Ocular anomalies, Primary Open-Angle Glaucoma (POAG). Every test must be completed before mating, and the result must fall within the threshold defined by the regulation.
See breeders who have already uploaded their mandatory tests for verification.
View verified breeders