Megaoesophagus, MCHR2-related(ME)
Also known as: MCHR2-related megaesophagus · Congenital megaesophagus · MCHR2-assoziierter Megaösophagus · Megaesophagus MCHR2
Overview
What it is
This is a hereditary condition of the digestive system where the esophagus, the muscular tube connecting the throat to the stomach, becomes abnormally stretched and loses its muscle tone. Because the esophagus cannot contract properly, it is unable to push food and liquids down into the stomach. This specific genetic form of the condition is associated with German Shepherds.
How it presents
Symptoms typically become noticeable in puppies when they begin transitioning to solid food. Owners will usually observe the effortless regurgitation of undigested food, excessive drooling, coughing, and a failure to grow at a normal rate.
Treatment
There is no cure, and the condition requires lifelong daily management, such as feeding the dog in an upright position. Managing the disease and treating common complications like lung infections typically costs between €3,000 and €12,000.
How it's tested
MCHR2-Megaösophagus DNA-Test(ME (MCHR2))
Primary testDNA testDer DNA-Test identifiziert die Mutation im MCHR2-Gen, die für die erbliche Form des Megaösophagus (Speiseröhrenerweiterung) verantwortlich ist.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Megaoesophagus, MCHR2-related?
This is a hereditary condition of the digestive system where the esophagus, the muscular tube connecting the throat to the stomach, becomes abnormally stretched and loses its muscle tone. Because the esophagus cannot contract properly, it is unable to push food and liquids down into the stomach. This specific genetic form of the condition is associated with German Shepherds.
How is Megaoesophagus, MCHR2-related tested?
Tests currently in our database: MCHR2-Megaösophagus DNA-Test.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.