Immunoglobulin G deficiency(IgGD)
Also known as: Selective IgG deficiency · IgG-Mangel · Immunoglobulin G Mangel · Selective Immunoglobulin G Deficiency · Hypogammaglobulinemia
Overview
What it is
This condition is a deficiency of Immunoglobulin G (IgG), which are the primary antibodies circulating in a dog's blood to fight off infections. Without enough of these protective proteins, the immune system cannot properly identify and destroy invading bacteria and viruses. This leaves the dog's entire body highly vulnerable to recurrent and severe infections.
How it presents
Owners typically notice frequent, severe infections of the respiratory tract, skin, or digestive system starting when the dog is a puppy or young juvenile. These infections often return quickly even after standard treatment.
Treatment
While the condition is incurable and requires lifelong management, symptoms can be managed with ongoing antibiotics and supportive care, sometimes including plasma or immunoglobulin therapies. Lifetime treatment costs typically range from 3,000 to 12,000 EUR.
How it's tested
Quantitative Immunglobulin-G-Bestimmung(IgG-Messung)
Primary testClinical examDer Test bestimmt die Konzentration von Immunglobulin G (IgG) im Blutserum mittels ELISA oder radialer Immundiffusion, um einen Mangel nachzuweisen.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Immunoglobulin G deficiency?
This condition is a deficiency of Immunoglobulin G (IgG), which are the primary antibodies circulating in a dog's blood to fight off infections. Without enough of these protective proteins, the immune system cannot properly identify and destroy invading bacteria and viruses. This leaves the dog's entire body highly vulnerable to recurrent and severe infections.
How is Immunoglobulin G deficiency tested?
Tests currently in our database: Quantitative Immunglobulin-G-Bestimmung.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.