Factor VII Deficiency(F7)
Also known as: Faktor-VII-Mangel · FVII deficiency · Hypoproconvertinemia · F7-Defizienz
Overview
What it is
Factor VII deficiency is an inherited blood clotting disorder affecting the circulatory system. It occurs when the body does not produce enough Factor VII, which is a specific protein essential for forming blood clots. Without enough of this protein, the normal process that stops bleeding is delayed, leading to prolonged bleeding after injuries or medical procedures.
How it presents
Most affected dogs show no symptoms in daily life and live normally, with the condition often remaining unnoticed until adulthood. An owner might only observe signs if the dog experiences unusually prolonged bleeding after a minor cut, dental cleaning, or surgery.
Treatment
The condition is not curable but is highly manageable, requiring no daily or lifelong medication. If surgery is necessary, preventative clotting support or blood products may be needed, typically costing between 200 and 1500 EUR per event.
How it's tested
Faktor-VII-Mangel DNA-Test(F7)
Primary testDNA testEin molekularbiologischer DNA-Test zum Nachweis der ursächlichen Mutation im F7-Gen, der Anlageträger und betroffene Hunde zuverlässig identifiziert.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
18 of 18 breeds
Mandatory testDeerhoundMandated by SDCA / CHIC
Mandatory testMiniature American Shepherd
RecommendedAlaskan Husky
RecommendedAlaskan Klee Kai
RecommendedBeagle
RecommendedBernese Hound
RecommendedEstonian Hound
RecommendedItalian Greyhound
RecommendedPetit Gascon Saintongeois
RecommendedPhalene, Continental Toy Spaniel
RecommendedPolish Hunting Dog
RecommendedPosavac Hound
RecommendedRedbone Coonhound
RecommendedSmall Bernese Hound
RecommendedSmall Schwyz Hound
RecommendedSmall Swiss Hound (Bernese)
RecommendedSmall Swiss Hound (Jura)
OptionalSussex Spaniel
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Factor VII Deficiency?
Factor VII deficiency is an inherited blood clotting disorder affecting the circulatory system. It occurs when the body does not produce enough Factor VII, which is a specific protein essential for forming blood clots. Without enough of this protein, the normal process that stops bleeding is delayed, leading to prolonged bleeding after injuries or medical procedures.
How is Factor VII Deficiency tested?
Tests currently in our database: Faktor-VII-Mangel DNA-Test.
Which breeds are most affected?
Most commonly affected: Deerhound, Miniature American Shepherd, Alaskan Husky, Alaskan Klee Kai, Beagle, Bernese Hound, Estonian Hound, Italian Greyhound.