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Health Testing Guide
Which tests are mandatory, how to spot responsible breeders — and what it costs when things go wrong.
For the Alaskan Husky we have compiled 2 mandatory and 3 recommended health tests, drawn from breed-club regulations, the University of PEI (CIDD), and OMIA — weighted by severity and heritability.
What this grade means
As an extremely high-performance working dog, the Alaskan Husky benefits from a high level of genetic diversity and is very robust compared to pure show breeds. Nevertheless, there are specific risks such as the fatal neurological condition Alaskan Husky Encephalopathy (AHE) as well as Progressive Retinal Atrophy (PRA), which can lead to blindness. Since there are no strict kennel club requirements for this breed, buyers must independently ensure that the parent dogs have been tested for these hereditary diseases.
Every breed is susceptible to certain inherited conditions. Just like humans, dogs inherit predispositions from their parents. Responsible breeders screen their breeding dogs for these conditions and make informed mating decisions to reduce the risk passed on to puppies.
No — but it's the strongest tool we have. Diet, exercise, environment, and genetics all contribute to whether a dog develops a condition. When breeders use the right tests to identify risk in potential parents, the likelihood of many conditions appearing in the puppies drops significantly.
There's no one-size-fits-all here. For the Alaskan Husky we track 2 mandatory tests plus 3 additional recommended ones. The specific tests and passing thresholds are detailed further below.
Keep in mind
Reliable screening tests still don't exist for many hereditary conditions, and tests for complex polygenic conditions are not always predictive of severity in the puppies. Even so, they're a powerful tool used by every responsible breeder.
There are two main types of health tests:
Screen the dog's DNA for known disease-causing mutations. Can be performed from puppyhood and give a binary result (clear / carrier / affected).
Clinical and imaging exams like X-ray, ultrasound, or ophthalmoscopy. They show how a predisposition actually manifests — usually only conclusive after 12–18 months.
We group breeding programs into three levels based on testing depth. Ask your breeder directly which level they meet.
A breeder at the Great level performs all mandatory tests plus 3 additional clinically recommended screenings that reduce risk in this breed.
In addition to mandatory tests:
Factor VII Deficiency(F7)
Herz und Kreislauf
Factor VII deficiency is an inherited blood clotting disorder affecting the circulatory system. It occurs when the body does not produce enough Factor VII, which is a specific protein essential for forming blood clots. Without enough of this protein, the normal process that stops bleeding is delayed, leading to prolonged bleeding after injuries or medical procedures.
Koerperfluessigkeiten · Passing: Clear or Carrier
GM1 Gangliosidosis(GM1)
Nervensystem
GM1 gangliosidosis is an inherited lysosomal storage disease that primarily affects the nervous system. It occurs when a deficiency in a specific enzyme, beta-galactosidase, prevents the body from breaking down certain fatty sugar compounds. Over time, these compounds build up to toxic levels inside cells, causing progressive damage to the brain and spinal cord.
Passing: Clear or Carrier
X-linked Progressive Retinal Atrophy(XLPRA1)
X-linked Progressive Retinal Atrophy is an inherited eye disease that causes the gradual breakdown of the retina, which is the light-sensitive tissue at the back of the eye. This degeneration affects the photoreceptor cells, which are the specialized cells responsible for detecting light. Over time, the loss of these cells leads to complete blindness.
Passing: CLEAR
These levels are a comparison framework, not an official certification. They help compare breeding programs at a glance.
A complete checklist with every mandatory and recommended test plus identity and rearing questions — take it with you.
Open the full checklistFor breeders
Machine-readable mating rules, minimum ages, scoring schemes, and what's required for HonestDog verification — as a printable guide.
Example rule — Achromatopsia-3, CNGB3-related
Both parents must be Clear or Carrier or better.
We compile mandatory tests from official breed regulations and veterinary databases — and check every uploaded certificate for authenticity.
L1 = mandatory under breed-club regulations. L2 = recommended or clinically indicated. L3 = lower prevalence. Every assignment carries a source and confidence rating.
VDH breeding regulations, CIDD (University of PEI), OMIA (University of Sydney), curated veterinary input.
Uploaded certificates are AI-extracted and reviewed by our team for authenticity, date, and result.
2 tests are currently mandatory under the relevant breed-club regulations. The most common are Achromatopsia-3, CNGB3-related (ACHM), Alaskan Husky Encephalopathy (AHE). Every test must be completed before mating, and the result must fall within the threshold defined by the regulation.
See breeders who have already uploaded their mandatory tests for verification.
View verified breeders