Exercise-induced metabolic myopathy(EIMM)
Also known as: Belastungsinduzierte metabolische Myopathie · Metabolische Myopathie · Exercise-induced myopathy · Very long-chain acyl-CoA dehydrogenase deficiency · VLCAD deficiency · …
Overview
What it is
This is an inherited metabolic disorder affecting the muscles, specifically linked to a genetic enzyme defect known as VLCAD deficiency or ACADVLD. In affected dogs, the muscle cells cannot properly break down certain fats to generate energy during physical exertion. This condition is highly breed-specific to the German Hunting Terrier.
How it presents
Symptoms typically appear at a young age, showing up during or shortly after physical activity. Owners will notice signs such as extreme muscle weakness, stiffness, tremors, or sudden collapse.
Treatment
There is no cure, but the condition can be managed long-term through lifelong exercise modification and dietary support. Lifetime management costs typically range from 1000 to 3500 EUR.
How it's tested
Exercise Induced Metabolic Myopathy (EIMM) DNA-Test(EIMM)
Primary testDNA testEin Gentest zur Identifizierung von Trägern und betroffenen Hunden für die belastungsinduzierte metabolische Myopathie, um eine Fehlfunktion des Muskelstoffwechsels unter Belastung frühzeitig zu erkennen.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Exercise-induced metabolic myopathy?
This is an inherited metabolic disorder affecting the muscles, specifically linked to a genetic enzyme defect known as VLCAD deficiency or ACADVLD. In affected dogs, the muscle cells cannot properly break down certain fats to generate energy during physical exertion. This condition is highly breed-specific to the German Hunting Terrier.
How is Exercise-induced metabolic myopathy tested?
Tests currently in our database: Exercise Induced Metabolic Myopathy (EIMM) DNA-Test.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.