Cerebellar abiotrophy(CA)
Also known as: Cerebelläre Abiotrophie · Cerebellar cortical abiotrophy · CCA · Kleinhirnabiotrophie · Cortical cerebellar degeneration · …
Overview
What it is
Cerebellar abiotrophy is an inherited neurological disorder affecting the brain, specifically the cerebellum, which regulates balance and movement coordination. In affected dogs, the nerve cells in this region prematurely degenerate and die off. This progressive cell loss disrupts the brain's ability to control smooth physical movements.
How it presents
Symptoms typically appear between a few weeks and a few months of age, starting with a wobbly gait, head tremors, and frequent falling. These balance and coordination issues steadily worsen over time.
Treatment
There is no cure for this progressive condition, and care is focused on supportive management or eventual euthanasia. Associated diagnostic and palliative costs typically range from 500 to 2500 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Cerebelläre Abiotrophie DNA-Test(CA)
Primary testDNA testDieser DNA-Test identifiziert die genetische Mutation, die für die cerebelläre Abiotrophie (CA) verantwortlich ist, und ermöglicht den Nachweis von Trägern und betroffenen Hunden.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
19 of 19 breeds
RecommendedAiredale Terrier
RecommendedAustralian Kelpie
RecommendedBeagle
RecommendedBernese Mountain Dog
RecommendedBorder Collie
RecommendedBrittany Spaniel
RecommendedBullmastiff
RecommendedChow Chow
RecommendedCoton de Tulear
RecommendedGordon Setter
RecommendedIrish Red Setter
RecommendedKerry Blue Terrier
RecommendedLabrador Retriever
RecommendedMiniature Poodle
RecommendedOld English Sheepdog
RecommendedParson Russell Terrier
RecommendedRhodesian Ridgeback
RecommendedSamoyed
RecommendedWorking Kelpie
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Cerebellar abiotrophy?
Cerebellar abiotrophy is an inherited neurological disorder affecting the brain, specifically the cerebellum, which regulates balance and movement coordination. In affected dogs, the nerve cells in this region prematurely degenerate and die off. This progressive cell loss disrupts the brain's ability to control smooth physical movements.
How is Cerebellar abiotrophy tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Cerebelläre Abiotrophie DNA-Test, Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Airedale Terrier, Australian Kelpie, Beagle, Bernese Mountain Dog, Border Collie, Brittany Spaniel, Bullmastiff, Chow Chow.