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Health Testing Guide
Which tests are mandatory, how to spot responsible breeders — and what it costs when things go wrong.
For the Old English Sheepdog we have compiled 10 mandatory and 9 recommended health tests, drawn from breed-club regulations, the University of PEI (CIDD), and OMIA — weighted by severity and heritability.
What this grade means
With 18 documented hereditary diseases, the Old English Sheepdog carries an above-average genetic burden, which requires great caution when purchasing a puppy. Hip dysplasia (HD) and severe neurological conditions such as epilepsy are particularly well-known risks for this breed. Furthermore, eye conditions like Collie Eye Anomaly (CEA) must be managed through consistent mandatory health tests to prevent vision impairment.
Every breed is susceptible to certain inherited conditions. Just like humans, dogs inherit predispositions from their parents. Responsible breeders screen their breeding dogs for these conditions and make informed mating decisions to reduce the risk passed on to puppies.
No — but it's the strongest tool we have. Diet, exercise, environment, and genetics all contribute to whether a dog develops a condition. When breeders use the right tests to identify risk in potential parents, the likelihood of many conditions appearing in the puppies drops significantly.
There's no one-size-fits-all here. For the Old English Sheepdog we track 10 mandatory tests plus 9 additional recommended ones. The specific tests and passing thresholds are detailed further below.
Keep in mind
Reliable screening tests still don't exist for many hereditary conditions, and tests for complex polygenic conditions are not always predictive of severity in the puppies. Even so, they're a powerful tool used by every responsible breeder.
There are two main types of health tests:
Screen the dog's DNA for known disease-causing mutations. Can be performed from puppyhood and give a binary result (clear / carrier / affected).
Clinical and imaging exams like X-ray, ultrasound, or ophthalmoscopy. They show how a predisposition actually manifests — usually only conclusive after 12–18 months.
We group breeding programs into three levels based on testing depth. Ask your breeder directly which level they meet.
A breeder at the Great level performs all mandatory tests plus 9 additional clinically recommended screenings that reduce risk in this breed.
In addition to mandatory tests:
Cleft palate
Allgemeine Fitness und Anatomie
A cleft palate is a congenital birth defect where the roof of the mouth fails to fuse properly during development in the womb. This failure leaves an abnormal opening between the oral cavity and the nasal passages. Because these two systems are directly connected, food, liquids, and air cannot be properly separated during swallowing.
Physisch · Passing: CLEAR
Immune-mediated hemolytic anemia (IMHA)(IMHA)
Andere
Immune-mediated hemolytic anemia (IMHA) is a severe condition where the dog's immune system mistakenly identifies its own red blood cells as foreign threats and destroys them. Because red blood cells are responsible for carrying oxygen, this destruction leads to a critical oxygen shortage throughout the body's organs. This disease primarily impacts the immune and circulatory systems.
Koerperfluessigkeiten · Passing: CLEAR
Progressive Retinal Atrophy (PRA)(PRA)
Augen
Progressive Retinal Atrophy (PRA) is an inherited eye disease that affects the retina, which is the light-sensitive layer of tissue at the back of the eye. In this condition, the specialized cells responsible for detecting light, known as photoreceptors, gradually degenerate and die. Because these cells cannot recover or be replaced, the disease slowly but inevitably leads to complete blindness.
Passing: CARRIER
Cervical vertebral compressive myelopathy(CVCM)
Bewegungsapparat
Cervical vertebral compressive myelopathy, commonly known as Wobbler syndrome, is a condition affecting the spine where the spinal cord in the neck becomes pinched. This compression is caused by malformed neck vertebrae or slipping discs between the bones. Over time, the constant pressure damages the nerve pathways that carry signals from the brain to the limbs.
Roentgen · Passing: Normal
Atrial septal defect(ASD)
Herz
An atrial septal defect is a congenital heart condition where a hole exists in the wall, called the septum, that separates the two upper chambers of the heart. This opening allows blood to flow abnormally between these chambers, which can gradually place extra strain on both the heart and the lungs.
Passing: NORMAL
Tricuspid valve dysplasia(TVD)
Herz und Kreislauf
Tricuspid valve dysplasia is a congenital heart defect where the tricuspid valve, located on the right side of the heart, does not develop normally. This valve normally acts as a one-way gate, but its malformation prevents it from closing properly. As a result, blood leaks backward into the right atrium instead of flowing forward to the lungs, forcing the heart to work much harder.
Ultraschall · Passing: NORMAL
Immune-mediated thrombocytopenia(IMT)
Immunsystem
Immune-mediated thrombocytopenia is an autoimmune disease where the dog's immune system mistakenly attacks and destroys its own blood platelets, which are cells essential for normal blood clotting. This destruction occurs primarily in the spleen and liver, leaving the body with too few platelets to stop bleeding. Without enough of these cells, spontaneous and potentially severe bleeding can occur throughout the body.
Koerperfluessigkeiten
Cerebellar abiotrophy(CA)
Nervensystem
Cerebellar abiotrophy is an inherited neurological disorder affecting the brain, specifically the cerebellum, which regulates balance and movement coordination. In affected dogs, the nerve cells in this region prematurely degenerate and die off. This progressive cell loss disrupts the brain's ability to control smooth physical movements.
DNA · Passing: CARRIER
Epilepsy(IE)
Nervensystem
Epilepsy is a chronic disorder of the brain and nervous system where abnormal electrical activity causes sudden, temporary disruptions in normal brain function. These disruptions lead to repeated seizures, which are involuntary changes in body movement, sensation, or behavior. Because the underlying cause is often complex, the brain's electrical signaling remains permanently prone to these sudden misfires.
Physisch · Passing: no epilepsy
These levels are a comparison framework, not an official certification. They help compare breeding programs at a glance.
A complete checklist with every mandatory and recommended test plus identity and rearing questions — take it with you.
Open the full checklistFor breeders
Machine-readable mating rules, minimum ages, scoring schemes, and what's required for HonestDog verification — as a printable guide.
Example rule — Primary ciliary dyskinesia (PCD), NME5-related
Both parents must be Clear/Carrier or better.
We compile mandatory tests from official breed regulations and veterinary databases — and check every uploaded certificate for authenticity.
L1 = mandatory under breed-club regulations. L2 = recommended or clinically indicated. L3 = lower prevalence. Every assignment carries a source and confidence rating.
VDH breeding regulations, CIDD (University of PEI), OMIA (University of Sydney), curated veterinary input.
Uploaded certificates are AI-extracted and reviewed by our team for authenticity, date, and result.
10 tests are currently mandatory under the relevant breed-club regulations. The most common are DNA-Identitätsnachweis, Zahn- und Bissbewertung, Primary ciliary dyskinesia (PCD), NME5-related (PCD). Every test must be completed before mating, and the result must fall within the threshold defined by the regulation.
See breeders who have already uploaded their mandatory tests for verification.
View verified breeders