Health Testing Guide
Which tests are mandatory, how to spot responsible breeders — and what it costs when things go wrong.
For the Miniature Poodle we have compiled 6 mandatory and 10 recommended health tests, drawn from breed-club regulations, the University of PEI (CIDD), and OMIA — weighted by severity and heritability.
What this grade means
The Zwergpudel receives a B grade because, despite some breed-specific risks, it is well-protected through consistent health testing. Key areas of concern include Progressive Retinal Atrophy (PRA-PRCD), which can lead to blindness, as well as patellar luxation. Buyers should always insist on seeing certified test results for the parents regarding these conditions, as well as for hereditary cataracts.
Every breed is susceptible to certain inherited conditions. Just like humans, dogs inherit predispositions from their parents. Responsible breeders screen their breeding dogs for these conditions and make informed mating decisions to reduce the risk passed on to puppies.
No — but it's the strongest tool we have. Diet, exercise, environment, and genetics all contribute to whether a dog develops a condition. When breeders use the right tests to identify risk in potential parents, the likelihood of many conditions appearing in the puppies drops significantly.
There's no one-size-fits-all here. For the Miniature Poodle we track 6 mandatory tests plus 10 additional recommended ones. The specific tests and passing thresholds are detailed further below.
Keep in mind
Reliable screening tests still don't exist for many hereditary conditions, and tests for complex polygenic conditions are not always predictive of severity in the puppies. Even so, they're a powerful tool used by every responsible breeder.
There are two main types of health tests:
Screen the dog's DNA for known disease-causing mutations. Can be performed from puppyhood and give a binary result (clear / carrier / affected).
Clinical and imaging exams like X-ray, ultrasound, or ophthalmoscopy. They show how a predisposition actually manifests — usually only conclusive after 12–18 months.
We group breeding programs into three levels based on testing depth. Ask your breeder directly which level they meet.
A breeder at the Great level performs all mandatory tests plus 10 additional clinically recommended screenings that reduce risk in this breed.
In addition to mandatory tests:
Immune-mediated hemolytic anemia (IMHA)(IMHA)
Andere
Immune-mediated hemolytic anemia (IMHA) is a severe condition where the dog's immune system mistakenly identifies its own red blood cells as foreign threats and destroys them. Because red blood cells are responsible for carrying oxygen, this destruction leads to a critical oxygen shortage throughout the body's organs. This disease primarily impacts the immune and circulatory systems.
Koerperfluessigkeiten
Lupus erythematosus (systemic, cutaneous/discoid)(SLE)
Haut und Fell
Lupus erythematosus is a severe autoimmune disease where the dog's immune system mistakenly attacks its own healthy tissues. In the cutaneous or discoid form, this damage is limited to the skin, while the systemic form can affect multiple internal organs, including the kidneys, joints, and blood vessels. This abnormal immune response causes chronic inflammation and tissue damage throughout the affected areas.
Koerperfluessigkeiten
Mitral valve dysplasia(MVD)
Herz
Mitral valve dysplasia is a congenital heart defect where the mitral valve, which acts as a one-way gate on the left side of the heart, does not form correctly. This malformation prevents the valve from closing tightly, allowing blood to leak backward instead of pumping efficiently to the body. Over time, this leakage strains the heart muscle, which can lead to heart enlargement and eventual heart failure.
Ultraschall
Patent ductus arteriosus (PDA)(PDA)
Herz
Patent ductus arteriosus is a congenital heart defect where a normal fetal blood vessel connecting the aorta and the pulmonary artery fails to close shortly after birth. This failure allows blood to continuously recirculate through the lungs instead of flowing to the rest of the body, putting severe, permanent strain on the heart muscle. Over time, this volume overload causes the left side of the heart to enlarge and weaken.
Ultraschall
Pyruvate kinase (PK) deficiency(PKD)
Herz und Kreislauf
Pyruvate kinase (PK) deficiency is an inherited metabolic disorder affecting red blood cells, which lack a vital enzyme needed to produce energy. Without this enzyme, the red blood cells break down prematurely, leading to a severe shortage of oxygen-carrying cells, a condition known as chronic anemia. Over time, this constant cell destruction can cause secondary damage to organs like the liver and bone marrow.
DNA
Immune-mediated thrombocytopenia(IMT)
Immunsystem
Immune-mediated thrombocytopenia is an autoimmune disease where the dog's immune system mistakenly attacks and destroys its own blood platelets, which are cells essential for normal blood clotting. This destruction occurs primarily in the spleen and liver, leaving the body with too few platelets to stop bleeding. Without enough of these cells, spontaneous and potentially severe bleeding can occur throughout the body.
Koerperfluessigkeiten
Intervertebral disc disease(IVDD)
Nervensystem
Intervertebral Disc Disease (IVDD) is a degenerative condition affecting the spine, where the cushioning discs between the vertebrae harden and rupture. When these discs herniate, meaning they bulge or burst, they press against the spinal cord and surrounding nerves. This compression disrupts the nervous system, causing pain and potentially blocking signals between the brain and the limbs.
Cerebellar abiotrophy(CA)
Nervensystem
Cerebellar abiotrophy is an inherited neurological disorder affecting the brain, specifically the cerebellum, which regulates balance and movement coordination. In affected dogs, the nerve cells in this region prematurely degenerate and die off. This progressive cell loss disrupts the brain's ability to control smooth physical movements.
DNA
Epilepsy(IE)
Nervensystem
Epilepsy is a chronic disorder of the brain and nervous system where abnormal electrical activity causes sudden, temporary disruptions in normal brain function. These disruptions lead to repeated seizures, which are involuntary changes in body movement, sensation, or behavior. Because the underlying cause is often complex, the brain's electrical signaling remains permanently prone to these sudden misfires.
Physisch
Globoid cell leukodystrophy (galactocerebrosidosis)(GCL)
Nervensystem
Globoid cell leukodystrophy is an inherited metabolic disorder affecting the nervous system, caused by a deficiency in an essential enzyme. This deficiency leads to the buildup of harmful substances that destroy myelin, which is the protective sheath surrounding nerve fibers in the brain and spinal cord. Without this protective covering, the nerves cannot transmit signals properly, resulting in progressive neurological decline.
DNA
These levels are a comparison framework, not an official certification. They help compare breeding programs at a glance.
A complete checklist with every mandatory and recommended test plus identity and rearing questions — take it with you.
Open the full checklistFor breeders
Machine-readable mating rules, minimum ages, scoring schemes, and what's required for HonestDog verification — as a printable guide.
Example rule — Patellar Luxation
Both parents must be Grad 0 or Grad 1 or better.
We compile mandatory tests from official breed regulations and veterinary databases — and check every uploaded certificate for authenticity.
L1 = mandatory under breed-club regulations. L2 = recommended or clinically indicated. L3 = lower prevalence. Every assignment carries a source and confidence rating.
VDH breeding regulations, CIDD (University of PEI), OMIA (University of Sydney), curated veterinary input.
Uploaded certificates are AI-extracted and reviewed by our team for authenticity, date, and result.
6 tests are currently mandatory under the relevant breed-club regulations. The most common are Progressive rod-cone degeneration (PRCD-PRA) (PRA-prcd), Cataract (HC), Elbow Dysplasia (ED). Every test must be completed before mating, and the result must fall within the threshold defined by the regulation.
See breeders who have already uploaded their mandatory tests for verification.
View verified breeders