Cerebellar atrophy, EMC1-related
Also known as: EMC1-related cerebellar atrophy · Cerebellar cortical degeneration EMC1 · EMC1-associated cerebellar ataxia · Kleinhirnatrophie (EMC1)
Overview
What it is
This is an inherited neurological disease affecting the cerebellum, which is the brain's coordination center. It is characterized by granuloprival cerebellar cortical degeneration, a process where essential nerve cells in this part of the brain progressively waste away. This degeneration severely disrupts the dog's ability to control and coordinate its voluntary movements.
How it presents
Affected puppies or young dogs typically show signs of uncoordinated movement, balance issues, and head tremors that worsen when they attempt purposeful actions. These symptoms are progressive and become more noticeable over time.
Treatment
There is no cure for this severe condition, and management is limited to diagnostic confirmation and supportive care, costing between 500 and 2500 EUR. Due to the progressive nature of the disease, long-term care is focused on maintaining quality of life until euthanasia is necessary.
How it's tested
Cerebellar Atrophy (EMC1) DNA-Test(CA (EMC1))
Primary testDNA testEin molekulargenetischer Test zum Nachweis der Mutation im EMC1-Gen, die zu einer fortschreitenden Degeneration des Kleinhirns führt.
Issuing body: other
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Cerebellar atrophy, EMC1-related?
This is an inherited neurological disease affecting the cerebellum, which is the brain's coordination center. It is characterized by granuloprival cerebellar cortical degeneration, a process where essential nerve cells in this part of the brain progressively waste away. This degeneration severely disrupts the dog's ability to control and coordinate its voluntary movements.
How is Cerebellar atrophy, EMC1-related tested?
Tests currently in our database: Cerebellar Atrophy (EMC1) DNA-Test.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.