Stomatocytosis
Also known as: Hereditary Stomatocytosis · Stomatozytose · Hereditäre Stomatozytose · Erythrocyte Stomatocytosis · Chondrodysplasia and Stomatocytosis
Overview
What it is
Stomatocytosis is an inherited disorder of the red blood cells, which are responsible for carrying oxygen throughout the body. Due to a defect in the cell membrane, these cells deform into a mouth-like or bowl-like shape instead of their normal round form. Because these deformed cells are fragile, the body breaks them down prematurely, which can lead to a shortage of red blood cells, a condition known as anemia.
How it presents
Owners typically notice signs of anemia, such as pale gums, weakness, and rapid tiring during exercise, starting in puppyhood or young adulthood. In some breeds, like the Alaskan Malamute, it may also be accompanied by physical dwarfism.
Treatment
There is no cure for this lifelong condition, but it is often mild and managed with routine monitoring rather than aggressive therapy. Lifetime supportive care and veterinary check-ups typically cost between 500 and 3000 EUR.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Stomatocytosis?
Stomatocytosis is an inherited disorder of the red blood cells, which are responsible for carrying oxygen throughout the body. Due to a defect in the cell membrane, these cells deform into a mouth-like or bowl-like shape instead of their normal round form. Because these deformed cells are fragile, the body breaks them down prematurely, which can lead to a shortage of red blood cells, a condition known as anemia.
How is Stomatocytosis tested?
Various clinical and genetic tests are used depending on the breed and presentation.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.