Immunoproliferative (Basenji) enteropathy/lymphocytic-plasmacytic enteritis(IPE)
Also known as: Immunoproliferative Enteropathy · Basenji Enteropathy · Lymphocytic-Plasmacytic Enteritis · Basenji Diarrheal Syndrome
Overview
What it is
This is a severe, chronic inflammatory disease of the digestive tract, particularly affecting Basenjis. It occurs when the dog's immune system abnormally attacks the lining of the small intestine, preventing the body from properly absorbing nutrients and leading to a dangerous loss of proteins. A definitive diagnosis is typically confirmed through an intestinal biopsy (Darmbiopsie), which remains the gold standard clinical exam for this condition.
How it presents
Owners will typically notice chronic or recurring diarrhea, vomiting, and progressive weight loss, often starting in young to middle-aged adulthood. These symptoms are frequently triggered or worsened by stress, and affected dogs can become severely emaciated if left untreated.
Treatment
While the condition is incurable, it can be managed long-term with a strict specialized diet and lifelong immunosuppressive medications. Managing this chronic disease requires ongoing veterinary care, with lifetime treatment costs typically ranging from €3,000 to €12,000.
How it's tested
Histopathologische Untersuchung von Darmbiopsien(Darmbiopsie)
Primary testClinical examDie Diagnose wird durch eine histopathologische Untersuchung von Gewebeproben (Biopsien) des Darms gesichert, die mittels Endoskopie entnommen werden.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Affected breeds
1 of 1 breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Immunoproliferative (Basenji) enteropathy/lymphocytic-plasmacytic enteritis?
This is a severe, chronic inflammatory disease of the digestive tract, particularly affecting Basenjis. It occurs when the dog's immune system abnormally attacks the lining of the small intestine, preventing the body from properly absorbing nutrients and leading to a dangerous loss of proteins. A definitive diagnosis is typically confirmed through an intestinal biopsy (Darmbiopsie), which remains the gold standard clinical exam for this condition.
How is Immunoproliferative (Basenji) enteropathy/lymphocytic-plasmacytic enteritis tested?
Tests currently in our database: Histopathologische Untersuchung von Darmbiopsien.
Which breeds are most affected?
Most commonly affected: Basenji.