Health Testing Guide
Which tests are mandatory, how to spot responsible breeders — and what it costs when things go wrong.
For the Basenji we have compiled 3 mandatory and 6 recommended health tests, drawn from breed-club regulations, the University of PEI (CIDD), and OMIA — weighted by severity and heritability.
What this grade means
The Basenji is a primitive breed that requires an above-average number of mandatory health tests, which is why we have assigned it a grade of C. In particular, the treacherous Fanconi syndrome (a severe kidney disease) and Progressive Retinal Atrophy (PRA), which can lead to blindness, must be ruled out through consistent genetic testing of the parent dogs. In addition, hip dysplasia (HD) should be clarified via X-ray results before purchase to avoid future joint problems.
Every breed is susceptible to certain inherited conditions. Just like humans, dogs inherit predispositions from their parents. Responsible breeders screen their breeding dogs for these conditions and make informed mating decisions to reduce the risk passed on to puppies.
No — but it's the strongest tool we have. Diet, exercise, environment, and genetics all contribute to whether a dog develops a condition. When breeders use the right tests to identify risk in potential parents, the likelihood of many conditions appearing in the puppies drops significantly.
There's no one-size-fits-all here. For the Basenji we track 3 mandatory tests plus 6 additional recommended ones. The specific tests and passing thresholds are detailed further below.
Keep in mind
Reliable screening tests still don't exist for many hereditary conditions, and tests for complex polygenic conditions are not always predictive of severity in the puppies. Even so, they're a powerful tool used by every responsible breeder.
There are two main types of health tests:
Screen the dog's DNA for known disease-causing mutations. Can be performed from puppyhood and give a binary result (clear / carrier / affected).
Clinical and imaging exams like X-ray, ultrasound, or ophthalmoscopy. They show how a predisposition actually manifests — usually only conclusive after 12–18 months.
We group breeding programs into three levels based on testing depth. Ask your breeder directly which level they meet.
A breeder at the Great level performs all mandatory tests plus 6 additional clinically recommended screenings that reduce risk in this breed.
In addition to mandatory tests:
Progressive Retinal Atrophy (PRA)(PRA)
Augen
Progressive Retinal Atrophy (PRA) is an inherited eye disease that affects the retina, which is the light-sensitive layer of tissue at the back of the eye. In this condition, the specialized cells responsible for detecting light, known as photoreceptors, gradually degenerate and die. Because these cells cannot recover or be replaced, the disease slowly but inevitably leads to complete blindness.
Passing: Clear or Carrier
Corneal dystrophy(CD)
Augen und Sehvermögen
Corneal dystrophy is an inherited eye disorder where abnormal, opaque materials like fats or calcium build up in the cornea, which is the clear outer layer of the eye. This accumulation typically affects both eyes and is non-inflammatory, meaning it does not cause immediate swelling or redness. Over time, these deposits can disrupt the smooth surface of the eye.
Augen · Passing: CLEAR
Hip dysplasia(HD)
Bewegungsapparat
Hip dysplasia is an inherited skeletal disorder where the ball and socket of the hip joint do not fit together properly. Instead of sliding smoothly, the bones rub and grind against each other, wearing down the protective cartilage. Over time, this chronic friction causes joint instability, painful inflammation, and progressive arthritis, which is the gradual wear and tear of the joint.
Roentgen · Passing: B or better
Pyruvate kinase (PK) deficiency(PKD)
Herz und Kreislauf
Pyruvate kinase (PK) deficiency is an inherited metabolic disorder affecting red blood cells, which lack a vital enzyme needed to produce energy. Without this enzyme, the red blood cells break down prematurely, leading to a severe shortage of oxygen-carrying cells, a condition known as chronic anemia. Over time, this constant cell destruction can cause secondary damage to organs like the liver and bone marrow.
DNA · Passing: Clear or Carrier
Hypothyroidism
Hormonelles und Stoffwechsel
Hypothyroidism is an endocrine disorder where the thyroid gland, located in the neck, fails to produce enough thyroid hormones. These hormones are essential for regulating the body's metabolic rate, which is the speed at which cells convert nutrients into energy. When hormone levels are too low, the dog's entire metabolism slows down, affecting multiple organ systems.
Koerperfluessigkeiten · Passing: Normal
Immunoproliferative (Basenji) enteropathy/lymphocytic-plasmacytic enteritis(IPE)
Verdauung und Darm
This is a severe, chronic inflammatory disease of the digestive tract, particularly affecting Basenjis. It occurs when the dog's immune system abnormally attacks the lining of the small intestine, preventing the body from properly absorbing nutrients and leading to a dangerous loss of proteins. A definitive diagnosis is typically confirmed through an intestinal biopsy (Darmbiopsie), which remains the gold standard clinical exam for this condition.
Koerperfluessigkeiten · Passing: CARRIER
These levels are a comparison framework, not an official certification. They help compare breeding programs at a glance.
A complete checklist with every mandatory and recommended test plus identity and rearing questions — take it with you.
Open the full checklistFor breeders
Machine-readable mating rules, minimum ages, scoring schemes, and what's required for HonestDog verification — as a printable guide.
Example rule — Cataract
Both parents must be CLEAR or better.
We compile mandatory tests from official breed regulations and veterinary databases — and check every uploaded certificate for authenticity.
L1 = mandatory under breed-club regulations. L2 = recommended or clinically indicated. L3 = lower prevalence. Every assignment carries a source and confidence rating.
VDH breeding regulations, CIDD (University of PEI), OMIA (University of Sydney), curated veterinary input.
Uploaded certificates are AI-extracted and reviewed by our team for authenticity, date, and result.
3 tests are currently mandatory under the relevant breed-club regulations. The most common are Cataract (HC), Persistent pupillary membranes (PPM) (PPM), Fanconi syndrome (FS). Every test must be completed before mating, and the result must fall within the threshold defined by the regulation.
See breeders who have already uploaded their mandatory tests for verification.
View verified breeders