Coat colour, HPS3-related(HPS3)
Also known as: Cocoa coat color · French Bulldog cocoa · HPS3-related cocoa · Hermansky-Pudlak syndrome 3 dog · Cocoa brown
Overview
What it is
This genetic variant affects the HPS3 gene, which is involved in the pathway that produces pigment, or melanin, in a dog's coat. While mutations in this gene can cause systemic health issues in other species, in dogs it only alters the chemical structure of the pigment. This results in a distinct dark brown coat color, often referred to as 'cocoa', without affecting any other organ systems.
How it presents
Owners will notice a warm, dark brown coat color that is present from birth. Because this is a purely cosmetic variation, the dog will not show any physical symptoms, health impairments, or discomfort.
Treatment
No treatment is required because this condition does not cause any medical issues. There are no associated veterinary costs, resulting in an expected lifetime cost of 0 EUR.
How it's tested
Cocoa (HPS3) DNA-Test(Cocoa (HPS3))
Primary testDNA testEin Gentest analysiert das HPS3-Gen auf die spezifische Mutation, die fuer die Cocoa-Fellfarbe (dunkelbraun) bei Franzoesischen Bulldoggen verantwortlich ist.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Coat colour, HPS3-related?
This genetic variant affects the HPS3 gene, which is involved in the pathway that produces pigment, or melanin, in a dog's coat. While mutations in this gene can cause systemic health issues in other species, in dogs it only alters the chemical structure of the pigment. This results in a distinct dark brown coat color, often referred to as 'cocoa', without affecting any other organ systems.
How is Coat colour, HPS3-related tested?
Tests currently in our database: Cocoa (HPS3) DNA-Test.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.