Hereditary Footpad Hyperkeratosis (Irish Terrier & Kromfohrländer)(HFH)
Also known as: Hereditary Footpad Hyperkeratosis · Corny Feet · Digitale Hyperkeratose · Familial Footpad Hyperkeratosis · Familial Paw Pad Hyperkeratosis · …
Overview
What it is
Hereditary footpad hyperkeratosis, also known as palmoplantar hyperkeratosis, is an inherited skin disorder caused by an autosomal-recessive genetic mutation. It affects the outer layer of the skin on a dog's paw pads, causing an overproduction of keratin, which is the tough protective protein found in hair and nails. This leads to abnormally thick, hard, and inelastic pads that easily crack and split.
How it presents
Owners will typically notice symptoms in puppies between 4 and 8 weeks of age, starting with extremely hard, cracked paw pads and horn-like growths. Because these cracks are painful, affected dogs often develop a stiff, uncomfortable gait and may hesitate to walk on hard or uneven ground.
Treatment
There is no cure for this lifelong condition, so management requires daily paw care, including moisturizing ointments, trimming excess horn tissue, and using protective booties. Lifetime treatment costs, including managing secondary infections, typically range from €1,500 to €5,000.
How it's tested
Hereditäre Fußballenhyperkeratose (HFH) DNA-Test(HFH)
Primary testDNA testEin molekularbiologischer DNA-Test zum Nachweis der ursächlichen Mutation im FAM83G-Gen, die zur Verhornung der Fußballen führt.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
12 of 12 breeds
Mandatory testAiredale TerrierMandated by Klub für Terrier e.V.
Mandatory testAustralian TerrierMandated by Klub für Terrier von 1894 e. V.
Mandatory testBlack Russian TerrierMandated by Klub für Terrier e.V.
Mandatory testCairn TerrierMandated by Klub für Terrier e.V. (KfT)
Mandatory testIrish Terrier
Mandatory testJack Russell TerrierMandated by Klub für Terrier e.V.
Mandatory testLakeland TerrierMandated by Klub für Terrier e.V. von 1894
Mandatory testNorfolk TerrierMandated by Klub für Terrier von 1894 e.V.
Mandatory testNorwich TerrierMandated by Klub für Terrier von 1894 e.V.
Mandatory testScottish TerrierMandated by Klub für Terrier von 1894 e.V.
Mandatory testSkye TerrierMandated by Klub für Terrier von 1894 e.V.
Mandatory testToy Manchester TerrierMandated by Klub für Terrier e.V. von 1894
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Hereditary Footpad Hyperkeratosis (Irish Terrier & Kromfohrländer)?
Hereditary footpad hyperkeratosis, also known as palmoplantar hyperkeratosis, is an inherited skin disorder caused by an autosomal-recessive genetic mutation. It affects the outer layer of the skin on a dog's paw pads, causing an overproduction of keratin, which is the tough protective protein found in hair and nails. This leads to abnormally thick, hard, and inelastic pads that easily crack and split.
How is Hereditary Footpad Hyperkeratosis (Irish Terrier & Kromfohrländer) tested?
Tests currently in our database: Hereditäre Fußballenhyperkeratose (HFH) DNA-Test.
Which breeds are most affected?
Most commonly affected: Airedale Terrier, Australian Terrier, Black Russian Terrier, Cairn Terrier, Irish Terrier, Jack Russell Terrier, Lakeland Terrier, Norfolk Terrier.