Coat colour, brown, TYRP1-related(B-Locus)
Also known as: B Locus · Brown coat color · Chocolate locus · TYRP1 gene mutation · Braun-Färbung · …
Overview
What it is
This genetic variant affects the TYRP1 gene, which controls the production of the dark pigment eumelanin in the skin and hair. Instead of producing black pigment, the dog's body produces a brown pigment, commonly known as chocolate or liver. This is a natural genetic variation of the integumentary (skin and coat) system rather than a disease.
How it presents
From birth, affected dogs will display a brown coat along with brown noses, lips, and paw pads instead of black. This is a purely cosmetic trait that does not cause any health issues or physical symptoms.
Treatment
No treatment is required or medically necessary, as this is a normal and healthy color variation. The associated treatment cost is 0 EUR.
How it's tested
B-Lokus (Fellfarbe braun) DNA-Test(B-Lokus)
Primary testDNA testEin Gentest, der spezifische Varianten im TYRP1-Gen untersucht, um festzustellen, ob ein Hund die genetische Anlage für braunes Eumelanin (Fellfarbe Braun/Schokolade) trägt oder vererbt.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Coat colour, brown, TYRP1-related?
This genetic variant affects the TYRP1 gene, which controls the production of the dark pigment eumelanin in the skin and hair. Instead of producing black pigment, the dog's body produces a brown pigment, commonly known as chocolate or liver. This is a natural genetic variation of the integumentary (skin and coat) system rather than a disease.
How is Coat colour, brown, TYRP1-related tested?
Tests currently in our database: B-Lokus (Fellfarbe braun) DNA-Test.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.