Familial vasculopathy(FCV)
Also known as: Familial cutaneous vasculopathy · German Shepherd dog vasculopathy · GSD cutaneous vasculopathy · Cutaneous vasculitis
Overview
What it is
Familial vasculopathy is an inherited inflammatory disorder of the blood vessels, primarily affecting the skin. This genetic condition causes the immune system to mistakenly attack blood vessels, leading to restricted blood flow and tissue damage. Unlike other forms of vasculopathy, this specific familial type is inherited in an autosomal-recessive manner and primarily impacts German Shepherds.
How it presents
Symptoms typically appear in German Shepherd puppies between 6 and 8 weeks of age. Owners may notice fever, lethargy, painful swelling, and deep, slow-healing ulcers on the paw pads, ears, tail, and nose.
Treatment
While the condition is incurable, it can be managed with lifelong therapy including anti-inflammatory drugs, immunosuppressants, and wound care. The estimated cost for ongoing supportive treatment ranges from €1,500 to €6,000.
How it's tested
Affected breeds
2 of 2 breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is familial vasculopathy?
Familial vasculopathy is an inherited inflammatory disorder of the blood vessels, primarily affecting the skin. This genetic condition causes the immune system to mistakenly attack blood vessels, leading to restricted blood flow and tissue damage. Unlike other forms of vasculopathy, this specific familial type is inherited in an autosomal-recessive manner and primarily impacts German Shepherds.
How is familial vasculopathy tested?
Various clinical and genetic tests are used depending on the breed and presentation.
Which breeds are most affected?
Most commonly affected: Greyhound, German Shepherd.