Dentinogenesis imperfecta(DI)
Also known as: Hereditary opalescent dentin · Dentin-Strukturstörung · DSPP-Defekt
Overview
What it is
Dentinogenesis imperfecta is a hereditary dental disorder where the dentin, which is the sensitive inner structure of the teeth, fails to develop properly. This makes the teeth structurally weak and highly prone to wear and breakage. While it can occur on its own, it is often a secondary symptom of Osteogenesis Imperfecta (a genetic bone disorder), which is what current genetic panels actually screen for.
How it presents
Owners will typically notice symptoms in puppyhood, starting with a distinct yellowish-brown or bluish-gray discoloration of the teeth. These weakened teeth wear down rapidly, fracture easily, and can lead to painful infections of the tooth nerve.
Treatment
While the underlying condition cannot be cured, it is manageable through lifelong dental care, including protective sealants or extractions, costing between 1,500 and 5,000 EUR.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Dentinogenesis imperfecta?
Dentinogenesis imperfecta is a hereditary dental disorder where the dentin, which is the sensitive inner structure of the teeth, fails to develop properly. This makes the teeth structurally weak and highly prone to wear and breakage. While it can occur on its own, it is often a secondary symptom of Osteogenesis Imperfecta (a genetic bone disorder), which is what current genetic panels actually screen for.
How is Dentinogenesis imperfecta tested?
Various clinical and genetic tests are used depending on the breed and presentation.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.