Cerebral amyloid angiopathy(CAA)
Also known as: Zerebrale Amyloidangiopathie · Canine cerebral amyloid angiopathy · Hereditary cerebral amyloid angiopathy · Congophilic angiopathy · Zerebrale Amyloid-Angiopathie
Overview
What it is
Cerebral amyloid angiopathy is a condition affecting the brain's circulatory system where abnormal proteins, called amyloid, build up within the walls of the blood vessels. This accumulation weakens the vessels, which can lead to restricted blood flow, microbleeds, or strokes. In senior dogs, this condition mirrors the vascular and Alzheimer's-associated brain pathology seen in humans.
How it presents
Symptoms typically appear in senior dogs and manifest as progressive cognitive decline, such as disorientation, personality changes, or sudden neurological issues like seizures. Owners might notice their dog getting stuck in corners or failing to recognize familiar routines.
Treatment
The condition is incurable and requires lifelong symptomatic management, including blood-flow-enhancing medications and specialized nutrition. Lifetime care and monitoring typically cost between 1,500 and 6,000 EUR.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Cerebral amyloid angiopathy?
Cerebral amyloid angiopathy is a condition affecting the brain's circulatory system where abnormal proteins, called amyloid, build up within the walls of the blood vessels. This accumulation weakens the vessels, which can lead to restricted blood flow, microbleeds, or strokes. In senior dogs, this condition mirrors the vascular and Alzheimer's-associated brain pathology seen in humans.
How is Cerebral amyloid angiopathy tested?
Various clinical and genetic tests are used depending on the breed and presentation.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.