Canine Scott Syndrome (German Shepherd)(CSS)
Also known as: Scott Syndrome · Scott-Syndrom · Platelet procoagulant deficiency · TMEM16F-associated Scott Syndrome · Thrombozyten-Funktionsstörung Typ Scott
Overview
What it is
Canine Scott Syndrome is an inherited blood clotting disorder that affects the cardiovascular system, specifically the function of platelets, which are the blood cells responsible for stopping bleeding. In affected dogs, these platelets fail to properly bind the proteins needed to form a stable clot after an injury. This impairs the body's natural ability to stop bleeding, even though the overall number of platelets in the blood is normal.
How it presents
Affected dogs usually appear completely healthy in daily life, but they may experience prolonged, difficult-to-control bleeding during teething, minor injuries, or surgery. This abnormal bleeding is often first noticed during routine puppyhood procedures, such as spaying or neutering.
Treatment
Although the underlying genetic defect is lifelong and incurable, the condition can be managed by preventing injuries and avoiding unnecessary surgeries. If an accident or emergency surgery occurs, treatments like blood or plasma transfusions are required, with costs typically ranging from 500 to 4000 EUR.
How it's tested
Canine Scott Syndrome DNA-Test(CSS)
Primary testDNA testDer DNA-Test identifiziert die ursächliche Mutation im ANO6-Gen, welche für die gestörte Blutgerinnung beim Caninen Scott-Syndrom verantwortlich ist.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Canine Scott Syndrome (German Shepherd)?
Canine Scott Syndrome is an inherited blood clotting disorder that affects the cardiovascular system, specifically the function of platelets, which are the blood cells responsible for stopping bleeding. In affected dogs, these platelets fail to properly bind the proteins needed to form a stable clot after an injury. This impairs the body's natural ability to stop bleeding, even though the overall number of platelets in the blood is normal.
How is Canine Scott Syndrome (German Shepherd) tested?
Tests currently in our database: Canine Scott Syndrome DNA-Test.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.