Dental hypomineralization(DH)
Also known as: Raine Syndrome · Raine-Syndrom · Zahnhypomineralisation · FAM20C hypomineralization · Dental Hypomineralisation · …
Overview
What it is
This is an inherited dental disorder where the outer protective layer of the teeth, known as enamel, does not mineralize properly during development. Because the enamel remains soft and thin, the teeth lack their normal protective shield and are highly prone to damage. This genetic condition is inherited in an autosomal-recessive manner, meaning a puppy must inherit the mutated gene from both parents to be affected.
How it presents
Owners will typically notice symptoms when the permanent adult teeth emerge, usually around five to seven months of age. The teeth often appear yellowish-brown or discolored, wear down rapidly, and can cause visible discomfort or pain when the dog is chewing.
Treatment
While the condition cannot be cured, it is manageable through lifelong dental care, which may include protective sealants or tooth extractions under anesthesia. Managing this condition typically costs between 1,500 and 6,000 EUR over the dog's lifetime depending on the severity.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
1 of 1 breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Dental hypomineralization?
This is an inherited dental disorder where the outer protective layer of the teeth, known as enamel, does not mineralize properly during development. Because the enamel remains soft and thin, the teeth lack their normal protective shield and are highly prone to damage. This genetic condition is inherited in an autosomal-recessive manner, meaning a puppy must inherit the mutated gene from both parents to be affected.
How is Dental hypomineralization tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Border Collie.