Weimaraner immunodeficiency(WIS)
Also known as: Weimaraner Immunodeficiency Syndrome · Weimaraner-Immundefizienz-Syndrom · Selective IgA deficiency in Weimaraners · Weimaraner immunoglobulin deficiency
Overview
What it is
Weimaraner immunodeficiency is an inherited disorder of the immune system where affected dogs cannot produce enough antibodies, which are protective proteins needed to fight off illness. Without these antibodies, the dog's body struggles to defend itself against common bacterial and viral infections. This leads to frequent, severe infections throughout the body.
How it presents
Symptoms usually begin within the first few weeks to months of a puppy's life. Owners may notice recurrent fevers, persistent skin or joint inflammation, and chronic diarrhea.
Treatment
There is no cure for this condition, and management requires lifelong supportive care with antibiotics and anti-inflammatory medications. Lifetime treatment costs typically range from 2,500 to 12,000 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Weimaraner immunodeficiency?
Weimaraner immunodeficiency is an inherited disorder of the immune system where affected dogs cannot produce enough antibodies, which are protective proteins needed to fight off illness. Without these antibodies, the dog's body struggles to defend itself against common bacterial and viral infections. This leads to frequent, severe infections throughout the body.
How is Weimaraner immunodeficiency tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Short-haired Weimaraner, Weimaraner.

