Von Willebrand disease type II(vWD II)
Also known as: vWD Type 2 · vWD Typ II · Von-Willebrand-Erkrankung Typ II · VWF-Mangel Typ 2 · Von-Willebrand-Syndrom Typ II · …
Overview
What it is
Von Willebrand Disease Type II is an inherited bleeding disorder affecting the blood and circulatory system. It is caused by a structural defect in the von Willebrand factor, which is a crucial protein that helps blood platelets stick together to form clots. Because this protein does not function correctly, the dog's body cannot properly stop bleeding, a process known as hemostasis, after an injury.
How it presents
Symptoms typically appear at a young age, often during puppyhood. Owners may notice spontaneous nosebleeds, bleeding gums, blood in the urine or stool, or unusually prolonged bleeding after minor injuries and routine surgeries.
Treatment
This condition is lifelong and incurable, requiring careful management to prevent injuries. In emergencies or before surgeries, blood or plasma transfusions are necessary, with treatment costs typically ranging from 1,000 to 6,000 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
vWD Typ II DNA-Test(vWD II)
Primary testDNA testEin molekularbiologischer DNA-Test zum Nachweis der ursächlichen Mutation im VWF-Gen, die für die Von-Willebrand-Erkrankung Typ II verantwortlich ist.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Von Willebrand disease type II?
Von Willebrand Disease Type II is an inherited bleeding disorder affecting the blood and circulatory system. It is caused by a structural defect in the von Willebrand factor, which is a crucial protein that helps blood platelets stick together to form clots. Because this protein does not function correctly, the dog's body cannot properly stop bleeding, a process known as hemostasis, after an injury.
How is Von Willebrand disease type II tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), vWD Typ II DNA-Test, Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: German Wirehaired Pointer.