Uveodermatological syndrome(UDS)
Also known as: Vogt-Koyanagi-Harada-like syndrome · VKH-like syndrome · Uveodermatologisches Syndrom · Canine uveodermatologic syndrome · Dermal-uveitis syndrome
Overview
What it is
Uveodermatological syndrome is an autoimmune disorder where a dog's immune system mistakenly attacks its own pigment-producing cells, called melanocytes. This attack primarily targets the eyes and the skin, leading to severe internal eye inflammation and a loss of coloration. Because the body's defense system is targeting its own tissues, it causes ongoing damage to these specific organ systems.
How it presents
Owners typically notice symptoms in early adulthood, starting with painful, red, or cloudy eyes and sensitivity to light. This is often accompanied or followed by a distinct loss of color on the nose, lips, eyelids, and skin.
Treatment
The condition is incurable but manageable, requiring lifelong immunosuppressive therapy and regular eye examinations to prevent blindness. Lifetime treatment and monitoring costs typically range from €3,000 to €12,000.
How it's tested
ECVO Augenuntersuchung (DOK)(ECVO-DOK)
Primary testEye examAugenuntersuchung durch ECVO-zertifizierten Augentierarzt (Dortmunder Kreis). Erkennt PRA, Katarakt, Entropium, CEA, MPP, RD u.a.
Issuing body: ECVO
Result scheme: Eye-ECVO
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Uveodermatological syndrome?
Uveodermatological syndrome is an autoimmune disorder where a dog's immune system mistakenly attacks its own pigment-producing cells, called melanocytes. This attack primarily targets the eyes and the skin, leading to severe internal eye inflammation and a loss of coloration. Because the body's defense system is targeting its own tissues, it causes ongoing damage to these specific organ systems.
How is Uveodermatological syndrome tested?
Tests currently in our database: ECVO Augenuntersuchung (DOK).
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.