Transitional cell carcinoma(TCC)
Also known as: Übergangszellkarzinom · Urothelkarzinom · Urothelial carcinoma · Canine transitional cell carcinoma · Blasenkrebs beim Hund
Overview
What it is
Transitional cell carcinoma (TCC) is a severe, malignant cancer of the urinary tract, most commonly arising in the bladder or the urethra, which is the tube that carries urine out of the body. As the tumor grows, it invades the surrounding bladder wall and can block the normal flow of urine. This cancer is associated with complex genetic factors, including specific acquired mutations in the cells of the bladder.
How it presents
Symptoms typically appear in older dogs and include blood in the urine, straining or pain during urination, and frequent attempts to urinate. Because these signs look identical to a standard bladder infection, the disease is often diagnosed at an advanced stage.
Treatment
Although the cancer is generally incurable, it can be managed long-term with chemotherapy, anti-inflammatory medications, and palliative care to support quality of life. Managing this condition requires lifelong therapy, with typical veterinary costs ranging from €2,500 to €7,500.
How it's tested
CADET BRAF Mutationstest(BRAF)
Primary testDNA testDieser molekulargenetische Test detektiert die BRAF V595E-Mutation in im Urin ausgeschiedenen Tumorzellen zur Diagnose des Übergangszellkarzinoms.
Issuing body: other
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Transitional cell carcinoma?
Transitional cell carcinoma (TCC) is a severe, malignant cancer of the urinary tract, most commonly arising in the bladder or the urethra, which is the tube that carries urine out of the body. As the tumor grows, it invades the surrounding bladder wall and can block the normal flow of urine. This cancer is associated with complex genetic factors, including specific acquired mutations in the cells of the bladder.
How is Transitional cell carcinoma tested?
Tests currently in our database: CADET BRAF Mutationstest.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.