Deafness, LOXHD1-related
Also known as: LOXHD1-related deafness · LOXHD1-associated hearing loss · Early-onset adult deafness LOXHD1 · LOXHD1-Taubheit · LOXHD1 congenital sensorineural deafness · …
Overview
What it is
This is an inherited form of deafness affecting the inner ear, caused by a genetic mutation in the LOXHD1 gene. This gene is responsible for maintaining the structure and function of tiny hair cells in the ear that detect sound vibrations and send signals to the brain. Without properly functioning hair cells, the dog's ability to process sound is gradually lost.
How it presents
Owners typically notice signs of progressive hearing loss starting within the first few months of life or in early adulthood. Affected dogs may stop responding to their names, household noises, or squeaky toys, eventually becoming completely deaf.
Treatment
There is no cure for this genetic deafness, but dogs can adapt well to visual training methods like hand signals. While the condition itself cannot be medically treated, diagnostic testing and supportive care typically cost between 100 and 600 EUR.
How it's tested
BAER-Hörtest(BAER)
Primary testhearingBrainstem Auditory Evoked Response: objektiver Hörtest, erkennt einseitige und beidseitige Taubheit.
Issuing body: BAER
Result scheme: BAER
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Deafness, LOXHD1-related?
This is an inherited form of deafness affecting the inner ear, caused by a genetic mutation in the LOXHD1 gene. This gene is responsible for maintaining the structure and function of tiny hair cells in the ear that detect sound vibrations and send signals to the brain. Without properly functioning hair cells, the dog's ability to process sound is gradually lost.
How is Deafness, LOXHD1-related tested?
Tests currently in our database: BAER-Hörtest, Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.