Deafness, CDH23-related
Also known as: CDH23-related deafness · CDH23-associated hearing loss · Cadherin-23 deafness · CDH23-assoziierte Taubheit · Congenital sensory deafness CDH23
Overview
What it is
This is an inherited form of deafness affecting the inner ear, caused by a genetic mutation in the CDH23 gene. This mutation disrupts the development and function of the tiny sensory hair cells in the ear that normally convert sound waves into electrical signals for the brain. Without these functioning hair cells, the dog cannot perceive sound.
How it presents
Owners will typically notice that affected puppies do not respond to sounds, such as clapping, calling, or squeaky toys, from a very young age. This congenital deafness is usually apparent as soon as the puppy's ear canals open, around two to three weeks of life.
Treatment
There is no cure or medical treatment to restore hearing, but the condition is painless and does not affect the dog's physical health. Management focuses on specialized hand-signal training, with typical supportive care and diagnostic costs ranging from 150 to 600 EUR.
How it's tested
BAER-Hörtest(BAER)
Primary testhearingBrainstem Auditory Evoked Response: objektiver Hörtest, erkennt einseitige und beidseitige Taubheit.
Issuing body: BAER
Result scheme: BAER
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Deafness, CDH23-related?
This is an inherited form of deafness affecting the inner ear, caused by a genetic mutation in the CDH23 gene. This mutation disrupts the development and function of the tiny sensory hair cells in the ear that normally convert sound waves into electrical signals for the brain. Without these functioning hair cells, the dog cannot perceive sound.
How is Deafness, CDH23-related tested?
Tests currently in our database: BAER-Hörtest, Embark Breed + Health Panel, MyDogDNA Panel, Feragen Komplettpaket (rassespezifisch), Labogen Komplettpaket (rassespezifisch).
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.