Deafness, bilateral, and vestibular dysfunction, MYO7A-related(DINGS2)
Also known as: MYO7A-related deafness and vestibular dysfunction · MYO7A-associated bilateral deafness · MYO7A-Taubheit und vestibuläre Dysfunktion · Congenital sensorineural deafness and vestibular dysfunction MYO7A · Deafness with Vestibular Dysfunction 2 · …
Overview
What it is
This inherited inner ear disorder, also known as DINGS2, is caused by a genetic mutation in the MYO7A gene. The mutation disrupts the sensory hair cells in the inner ear that are responsible for transmitting sound and maintaining balance. Consequently, affected dogs suffer from complete hearing loss in both ears and a poorly functioning vestibular system.
How it presents
Symptoms usually appear within the first few weeks of life as puppies start moving around. Owners will typically notice complete deafness, a distinct head tilt, clumsy or uncoordinated walking, and general disorientation.
Treatment
There is no cure for this lifelong condition, meaning affected dogs require permanent lifestyle adjustments and a secure environment. While there is no medical treatment to restore hearing or balance, supportive care and safety measures typically cost between 300 and 1500 EUR.
How it's tested
MYO7A-assoziierte Taubheit und vestibuläre Dysfunktion Gentest(MYO7A)
Primary testDNA testEin DNA-Test identifiziert die Mutation im MYO7A-Gen, die für die bilaterale Taubheit und die vestibuläre Dysfunktion verantwortlich ist.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Deafness, bilateral, and vestibular dysfunction, MYO7A-related?
This inherited inner ear disorder, also known as DINGS2, is caused by a genetic mutation in the MYO7A gene. The mutation disrupts the sensory hair cells in the inner ear that are responsible for transmitting sound and maintaining balance. Consequently, affected dogs suffer from complete hearing loss in both ears and a poorly functioning vestibular system.
How is Deafness, bilateral, and vestibular dysfunction, MYO7A-related tested?
Tests currently in our database: MYO7A-assoziierte Taubheit und vestibuläre Dysfunktion Gentest.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.