Stiff skin syndrome(SSS)
Overview
What it is
Stiff skin syndrome is an inherited genetic disorder affecting the connective tissues, specifically the skin and the underlying fascia, which is the fibrous tissue enclosing the muscles. It causes a progressive hardening and loss of elasticity in these tissues, which severely restricts the dog's normal movement. This condition is inherited in an autosomal-recessive manner, meaning a puppy must inherit the mutated gene from both parents to be affected.
How it presents
Owners typically notice symptoms in puppies or young dogs, starting with skin that feels unusually thick, hard, and tight to the touch. As the disease progresses, the dog will develop joint stiffness, a rigid or wooden gait, and visible difficulty standing up, walking, or stretching.
Treatment
There is no cure for this progressive condition, so treatment focuses on lifelong management to maintain quality of life through physical therapy and pain relief. Managing this disease requires ongoing veterinary care, with lifetime costs typically ranging from 1,500 to 6,000 EUR.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Stiff skin syndrome?
Stiff skin syndrome is an inherited genetic disorder affecting the connective tissues, specifically the skin and the underlying fascia, which is the fibrous tissue enclosing the muscles. It causes a progressive hardening and loss of elasticity in these tissues, which severely restricts the dog's normal movement. This condition is inherited in an autosomal-recessive manner, meaning a puppy must inherit the mutated gene from both parents to be affected.
How is Stiff skin syndrome tested?
Various clinical and genetic tests are used depending on the breed and presentation.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.