Spongy Degeneration with Cerebellar Ataxia 2 (Belgian Malinois)(SDCA2)
Also known as: Spongiform degeneration with cerebellar ataxia subtype 2 · Spongiöse Degeneration mit zerebellärer Ataxie Typ 2 · Cerebellar ataxia subtype 2 · SDCA 2 · ATP1B2-associated ataxia · …
Overview
What it is
Spongiform Degeneration with Cerebellar Ataxia Type 2 (SDCA2) is an inherited neurological disease affecting the brain, specifically the cerebellum, which controls movement and balance. In affected dogs, the brain tissue develops microscopic, sponge-like holes, disrupting the normal transmission of nerve signals. This leads to a severe loss of motor coordination and control.
How it presents
Owners typically notice symptoms in puppies between 4 and 8 weeks of age, starting with uncoordinated movement, stumbling, and head tremors. These balance issues progress rapidly, making it difficult or impossible for the puppy to stand or walk.
Treatment
There is no cure for this progressive condition, and supportive care is focused on comfort before humane euthanasia is elected. Veterinary costs typically range from 200 to 800 EUR, which covers diagnostic confirmation and end-of-life care.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
SDCA2 (Spongy Degeneration with Cerebellar Ataxia Subtype 2) DNA-Test(SDCA2)
Primary testDNA testDieser Gentest identifiziert mittels DNA-Analyse die ursächliche Mutation im ATP1B2-Gen, welche für die spongiöse Degeneration mit zerebellärer Ataxie Typ 2 verantwortlich ist.
Issuing body: other
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Spongy Degeneration with Cerebellar Ataxia 2 (Belgian Malinois)?
Spongiform Degeneration with Cerebellar Ataxia Type 2 (SDCA2) is an inherited neurological disease affecting the brain, specifically the cerebellum, which controls movement and balance. In affected dogs, the brain tissue develops microscopic, sponge-like holes, disrupting the normal transmission of nerve signals. This leads to a severe loss of motor coordination and control.
How is Spongy Degeneration with Cerebellar Ataxia 2 (Belgian Malinois) tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), SDCA2 (Spongy Degeneration with Cerebellar Ataxia Subtype 2) DNA-Test, Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Dutch Shepherd, Dutch Shepherd (Longhair), Dutch Shepherd (Wire-Haired), Belgian Malinois.