Spongy Degeneration with Cerebellar Ataxia 1 (Belgian Malinois)(SDCA1)
Also known as: Spongiform degeneration with cerebellar ataxia 1 · Cerebellar ataxia Malinois type 1 · Spongiöse Degeneration mit zerebellarer Ataxie Typ 1 · KCNJ10-associated ataxia
Overview
What it is
Spongiöse Degeneration mit zerebellarer Ataxie 1 (SDCA1) is an inherited neurological disease that causes the brain tissue, particularly in the cerebellum, to break down and develop a spongy appearance. The cerebellum is the area of the brain responsible for coordinating voluntary movements and balance. As this tissue degenerates, the dog's nervous system loses the ability to properly control body movements.
How it presents
Symptoms typically appear in puppies between 4 and 8 weeks of age. Owners will notice a rapid onset of uncoordinated movements, severe balance issues, and muscle tremors.
Treatment
There is no cure for this progressive disease, and supportive care or diagnostic testing generally costs between 200 and 1000 EUR. Because of the severity and rapid progression of the condition, humane euthanasia is typically recommended shortly after diagnosis.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
2 of 2 breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Spongy Degeneration with Cerebellar Ataxia 1 (Belgian Malinois)?
Spongiöse Degeneration mit zerebellarer Ataxie 1 (SDCA1) is an inherited neurological disease that causes the brain tissue, particularly in the cerebellum, to break down and develop a spongy appearance. The cerebellum is the area of the brain responsible for coordinating voluntary movements and balance. As this tissue degenerates, the dog's nervous system loses the ability to properly control body movements.
How is Spongy Degeneration with Cerebellar Ataxia 1 (Belgian Malinois) tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Belgian Malinois, Dutch Shepherd.