Sensory Neuropathy(SN)
Also known as: Border Collie Sensory Neuropathy · Hereditary Sensory Neuropathy · SN-BC · RETREG1-related sensory neuropathy · FAM134B sensory neuropathy
Overview
What it is
Sensory neuropathy is an inherited neurological disorder where the sensory nerve cells, which transmit feelings of pain and touch to the brain, progressively break down. This degradation of the nervous system prevents the dog from properly feeling its own limbs. It is an autosomal-recessive condition, meaning a puppy must inherit the mutated gene from both parents to be affected.
How it presents
Symptoms typically appear between 2 and 7 months of age, starting with coordination problems and a reduced sensitivity to pain. Owners will often notice the dog excessively licking, biting, or chewing at its own paws, which can lead to severe self-inflicted injuries.
Treatment
There is no cure for this progressive condition, and treatment is limited to managing wounds and trying to prevent self-injury. Supportive care typically costs between 500 and 2500 EUR, though the severity of the self-mutilation often leads to early euthanasia.
How it's tested
Sensory Neuropathy (SN) DNA-Test(SN)
Primary testDNA testEin Gentest, der die ursächliche Mutation im RETREG1-Gen identifiziert, um betroffene Hunde, Träger und mutationsfreie Tiere zu bestimmen.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
1 of 1 breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Sensory Neuropathy?
Sensory neuropathy is an inherited neurological disorder where the sensory nerve cells, which transmit feelings of pain and touch to the brain, progressively break down. This degradation of the nervous system prevents the dog from properly feeling its own limbs. It is an autosomal-recessive condition, meaning a puppy must inherit the mutated gene from both parents to be affected.
How is Sensory Neuropathy tested?
Tests currently in our database: Sensory Neuropathy (SN) DNA-Test.
Which breeds are most affected?
Most commonly affected: Bracco Italiano.