Primary Ciliary Dyskinesia(RIPD)
Also known as: Recurrent pulmonary inflammation · Wiederkehrende entzündliche Lungenerkrankung · Recurrent inflammatory airway disease · Recurrent inflammatory pulmonary disease · Inflammatory Pulmonary Disease · …
Overview
What it is
This is an inherited respiratory disease passed down in an autosomal-recessive manner, meaning a puppy must inherit the gene variant from both parents to be affected. It is caused by a genetic variant in the AKNA gene, which leads to recurrent and severe inflammation of the lung tissue. The condition affects the respiratory system, impairing the lungs' ability to function properly and leading to frequent infections.
How it presents
Affected dogs typically show symptoms starting in puppyhood, often within the first few months of life. Owners will notice chronic coughing, thick nasal discharge, difficulty breathing, and repeated bouts of pneumonia.
Treatment
The condition is incurable and requires lifelong supportive care, including medications, nebulization, and frequent veterinary visits to manage infections. Lifetime management is costly, with treatment expenses typically ranging from 3,000 to 10,000 EUR.
How it's tested
Recurrent Inflammatory Pulmonary Disease (RIPD) DNA-Test(RIPD)
Primary testDNA testDer DNA-Test identifiziert die ursächliche Mutation im AK7-Gen bei Rough Collies, um Anlageträger und betroffene Hunde frühzeitig zu identifizieren.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Primary Ciliary Dyskinesia?
This is an inherited respiratory disease passed down in an autosomal-recessive manner, meaning a puppy must inherit the gene variant from both parents to be affected. It is caused by a genetic variant in the AKNA gene, which leads to recurrent and severe inflammation of the lung tissue. The condition affects the respiratory system, impairing the lungs' ability to function properly and leading to frequent infections.
How is Primary Ciliary Dyskinesia tested?
Tests currently in our database: Recurrent Inflammatory Pulmonary Disease (RIPD) DNA-Test.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.