Progressive ataxia with head tremor and seizures
Also known as: Spinocerebellar ataxia with seizures · Ataxie mit Kopftitubation und Krampfanfällen · Progressive cerebellar ataxia with head tremor and seizures · Ataxia, progressive, with head tremor and seizures
Overview
What it is
This is a severe, progressive disorder of the nervous system characterized by the premature death of nerve cells in the brain, particularly within the cerebellum, which controls balance and movement. The disease is associated with unusual microscopic structures, called inclusions, that build up inside these nerve cells. This cellular damage leads to a gradual loss of physical coordination and body control.
How it presents
Owners typically first notice an unsteady, swaying walk (ataxia) and involuntary head tremors during puppyhood or adolescence. Over time, these coordination issues worsen, and the dog may begin having uncontrollable seizures.
Treatment
There is no cure for this progressive condition, but supportive care and seizure medications can help manage symptoms temporarily. Lifelong management and diagnostic monitoring typically cost between €1,000 and €3,500.
How it's tested
PATHTS DNA-Test(PATHTS)
Primary testDNA testDer DNA-Test identifiziert die ursächliche Mutation im FNIP2-Gen, die für diese progressive neurologische Erkrankung verantwortlich ist, und ermöglicht den Nachweis von Trägern.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Progressive ataxia with head tremor and seizures?
This is a severe, progressive disorder of the nervous system characterized by the premature death of nerve cells in the brain, particularly within the cerebellum, which controls balance and movement. The disease is associated with unusual microscopic structures, called inclusions, that build up inside these nerve cells. This cellular damage leads to a gradual loss of physical coordination and body control.
How is Progressive ataxia with head tremor and seizures tested?
Tests currently in our database: PATHTS DNA-Test.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.