Squamous cell carcinoma of the digit(SCC)
Also known as: Digital squamous cell carcinoma · Plattenepithelkarzinom der Zehe · Subunguales Plattenepithelkarzinom · Nailbed squamous cell carcinoma · Toe cancer in dogs · …
Overview
What it is
This is a malignant (cancerous) tumor of the skin cells that develops in the toe area, typically starting in the nail bed. It is a severe condition that can invade and destroy the surrounding bone of the digit if left untreated. In Poodles and Giant Schnauzers, a specific genetic variation in the KITLG gene is known to increase the risk of developing this cancer.
How it presents
Owners typically notice persistent limping, swelling of a toe, recurring nail bed infections, or the sudden loss of a claw. These symptoms most commonly appear in middle-aged to older dogs.
Treatment
Treatment is usually a one-time surgical amputation of the affected toe, which can be curative if performed before the cancer spreads. The total cost for diagnostics, surgery, and biopsy analysis typically ranges from 1,500 to 5,000 EUR.
How it's tested
KITLG (Plattenepithelkarzinom der Zehe)(SCD)
Primary testDNA testDer Gentest analysiert eine Kopienzahlvariante im KITLG-Gen, die mit einem stark erhoehten Risiko fuer die Entstehung von Plattenepithelkarzinomen an den Zehen bei bestimmten Rassen assoziiert ist.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Squamous cell carcinoma of the digit?
This is a malignant (cancerous) tumor of the skin cells that develops in the toe area, typically starting in the nail bed. It is a severe condition that can invade and destroy the surrounding bone of the digit if left untreated. In Poodles and Giant Schnauzers, a specific genetic variation in the KITLG gene is known to increase the risk of developing this cancer.
How is Squamous cell carcinoma of the digit tested?
Tests currently in our database: KITLG (Plattenepithelkarzinom der Zehe).
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.