Persistent Müllerian Duct Syndrome(PMDS)
Also known as: Müller-Gang-Persistenz · Persistierender Müller-Gang · Canine PMDS · Müllerian Duct Syndrome · Müllerian Duct Persistence · …
Overview
What it is
Persistent Müllerian Duct Syndrome (PMDS) is a genetic disorder of the reproductive system in male dogs. It occurs when the internal female reproductive tract, including the uterus, fails to break down during embryonic development and remains present alongside male organs. Affected dogs are genetically male and typically have normal external male anatomy, but carry these hidden internal female structures.
How it presents
Owners usually first notice signs in young dogs, often when one or both testicles fail to descend into the scrotum. Over time, the retained internal organs can lead to complications like abdominal pain, urinary tract infections, or testicular tumors as the dog matures.
Treatment
The condition is treatable through a one-time surgical procedure to remove both the retained testicles and the abnormal uterine tissue. This surgery typically costs between 800 and 2500 EUR and prevents future life-threatening infections or cancers.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Persistent Müllerian Duct Syndrome (PMDS) DNA-Test(PMDS)
Primary testDNA testEin DNA-Test, der die ursächliche Mutation im AMHR2-Gen nachweist, um betroffene Hunde, Anlageträger und mutationsfreie Tiere zu identifizieren.
Issuing body: other
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Persistent Müllerian Duct Syndrome?
Persistent Müllerian Duct Syndrome (PMDS) is a genetic disorder of the reproductive system in male dogs. It occurs when the internal female reproductive tract, including the uterus, fails to break down during embryonic development and remains present alongside male organs. Affected dogs are genetically male and typically have normal external male anatomy, but carry these hidden internal female structures.
How is Persistent Müllerian Duct Syndrome tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Persistent Müllerian Duct Syndrome (PMDS) DNA-Test, Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.