Parkinson disease, PARK7-related
Also known as: PARK7-associated Parkinsonism · PARK7-related Parkinson's disease · DJ1-related Parkinson's disease · Parkinson-Krankheit (PARK7) · Canine Parkinsonism PARK7
Overview
What it is
This is a severe, inherited neurological disorder affecting the brain and nervous system. A genetic mutation in the PARK7 gene leads to the progressive loss of specialized nerve cells that are responsible for controlling and coordinating body movements. Over time, this cellular damage impairs the brain's ability to transmit smooth signals to the muscles.
How it presents
Owners typically notice symptoms starting in early to middle adulthood, which include muscle stiffness, tremors, slowed movements, and a progressive loss of coordination. The dog may have difficulty walking or maintaining balance as the condition advances.
Treatment
There is no cure for this progressive disease, meaning treatment focuses entirely on lifelong supportive care and managing symptoms. The lifetime cost for supportive therapies, medications, and veterinary monitoring typically ranges from 3,000 to 12,000 EUR.
How it's tested
PARK7-Parkinson-Krankheit DNA-Test(PARK7)
Primary testDNA testDer DNA-Test identifiziert die ursächliche Mutation im PARK7-Gen, welche für die autosomal-rezessive Parkinson-Erkrankung beim Hund verantwortlich ist.
Issuing body: other
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Parkinson disease, PARK7-related?
This is a severe, inherited neurological disorder affecting the brain and nervous system. A genetic mutation in the PARK7 gene leads to the progressive loss of specialized nerve cells that are responsible for controlling and coordinating body movements. Over time, this cellular damage impairs the brain's ability to transmit smooth signals to the muscles.
How is Parkinson disease, PARK7-related tested?
Tests currently in our database: PARK7-Parkinson-Krankheit DNA-Test.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.