Muscle hypertrophy, dysphagia, and gait abnormalities
Also known as: Muscular dystrophy with muscle hypertrophy, dysphagia, and gait abnormalities · Muskelhypertrophie, Dysphagie und Gangstörungen
Overview
What it is
This is an inherited muscle disorder, or myopathy, that affects the skeletal muscles responsible for movement and swallowing. It is caused by genetic mutations that disrupt normal muscle cell structure, leading to abnormal muscle enlargement and a loss of normal function.
How it presents
Symptoms typically appear during puppyhood, with owners noticing an unusually bulky or muscular build and a stiff, wooden way of walking. Affected dogs also have severe difficulty swallowing, which can lead to drooling, gagging, and coughing after eating or drinking.
Treatment
There is no cure for this progressive condition, and treatment is limited to lifelong supportive care to manage symptoms and prevent complications like aspiration pneumonia. Lifetime management costs generally range from €2,500 to €10,000.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Muscle hypertrophy, dysphagia, and gait abnormalities?
This is an inherited muscle disorder, or myopathy, that affects the skeletal muscles responsible for movement and swallowing. It is caused by genetic mutations that disrupt normal muscle cell structure, leading to abnormal muscle enlargement and a loss of normal function.
How is Muscle hypertrophy, dysphagia, and gait abnormalities tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.