Canine Multiple System Degeneration (Kerry Blue Terrier)(CMSD)
Also known as: Canine Multiple System Degeneration · Cerebellar and Multiple System Degeneration · Multisystemdegeneration · Cerebelläre Ataxie des Kerry Blue Terriers
Overview
What it is
Canine Multiple System Degeneration, also known as Progressive Neuronal Abiotrophy, is a severe inherited neurological disease that affects the brain. It causes the progressive premature death of nerve cells, particularly in the cerebellum, which is the area responsible for coordinating movement. Because it is an autosomal-recessive condition, a dog must inherit the mutated gene from both parents to develop the disease.
How it presents
Symptoms typically appear between 2 and 6 months of age, starting with a lack of coordination, head tremors, and stiff movements. These signs rapidly progress to a severe loss of mobility, making it difficult or impossible for the dog to walk.
Treatment
There is no cure for this condition, and treatment is limited to supportive veterinary care and diagnostic testing. Costs generally range from 300 to 1500 EUR, and because the disease is progressive and fatal, early euthanasia is often necessary to prevent suffering.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Canine Multiple System Degeneration (Kerry Blue Terrier)?
Canine Multiple System Degeneration, also known as Progressive Neuronal Abiotrophy, is a severe inherited neurological disease that affects the brain. It causes the progressive premature death of nerve cells, particularly in the cerebellum, which is the area responsible for coordinating movement. Because it is an autosomal-recessive condition, a dog must inherit the mutated gene from both parents to develop the disease.
How is Canine Multiple System Degeneration (Kerry Blue Terrier) tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.