May-Hegglin anomaly(MHA)
Also known as: May-Hegglin-Anomalie · MYH9-related thrombocytopenia · MYH9-assoziierte Thrombozytopenie · Macrothrombocytopenia with leukocyte inclusions
Overview
What it is
May-Hegglin Anomaly is an inherited blood disorder affecting platelets, which are the cells responsible for clotting, and white blood cells. It causes the body to produce abnormally large platelets, often accompanied by a lower overall platelet count. This genetic condition is mild and primarily impacts the blood-forming system rather than other major organs.
How it presents
Most affected dogs show no visible symptoms and live completely normal lives, with the condition usually discovered during routine blood tests at any age. In very rare cases, an owner might notice a slightly increased tendency to bruise or bleed.
Treatment
No active treatment or lifelong therapy is required for this condition. Owners should expect to spend approximately 100 to 500 EUR on diagnostic blood tests and precautionary veterinary consultations prior to any planned surgeries.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is May-Hegglin anomaly?
May-Hegglin Anomaly is an inherited blood disorder affecting platelets, which are the cells responsible for clotting, and white blood cells. It causes the body to produce abnormally large platelets, often accompanied by a lower overall platelet count. This genetic condition is mild and primarily impacts the blood-forming system rather than other major organs.
How is May-Hegglin anomaly tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.