Macrothrombocytopenia(MTC)
Also known as: Congenital Macrothrombocytopenia · Inherited Macrothrombocytopenia · TUBB1 Macrothrombocytopenia · Benign Thrombocytopenia · Macrothrombocytopenia of Cavalier King Charles Spaniels · …
Overview
What it is
Macrothrombocytopenia is a harmless, inherited blood condition where a dog has fewer but much larger blood platelets, also known as thrombocytes. Platelets are specialized cell fragments in the circulatory system that help the blood clot to stop bleeding. Despite the lower overall platelet count, the larger size of these cells compensates for the difference, allowing the blood to clot normally.
How it presents
This condition is entirely asymptomatic, meaning affected dogs show no physical signs of illness at any age. It is typically discovered by chance during routine blood work, which can happen at any point in the dog's life.
Treatment
No treatment is required because this is a completely benign trait that does not impact health. Any associated costs, typically ranging from 0 to 250 EUR, are limited to one-time diagnostic blood tests to rule out other conditions.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Macrothrombocytopenia?
Macrothrombocytopenia is a harmless, inherited blood condition where a dog has fewer but much larger blood platelets, also known as thrombocytes. Platelets are specialized cell fragments in the circulatory system that help the blood clot to stop bleeding. Despite the lower overall platelet count, the larger size of these cells compensates for the difference, allowing the blood to clot normally.
How is Macrothrombocytopenia tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.