Lysosomal storage disease, CNP-related(LSD)
Also known as: CNP-related lysosomal storage disease · CNP-LSD · Lysosomale Speicherkrankheit (CNP-Gen) · Lysosomal storage disease associated with CNP · CNP-deficiency lysosomal storage disease
Overview
What it is
This hereditary metabolic disorder is caused by a genetic defect that prevents cells from properly breaking down cellular waste. This waste builds up inside the cells, particularly in the brain and nervous system, leading to progressive damage. Over time, this accumulation disrupts normal neurological functions.
How it presents
Symptoms typically appear in puppies or young dogs and include noticeable coordination problems, tremors, vision loss, and behavioral changes. These neurological signs steadily worsen over time.
Treatment
There is no cure for this condition, and treatment is limited to supportive care to keep the dog comfortable. Managing this progressive disease through palliative care typically costs between €1,000 and €3,500 over the dog's remaining lifespan.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Lysosomal storage disease, CNP-related?
This hereditary metabolic disorder is caused by a genetic defect that prevents cells from properly breaking down cellular waste. This waste builds up inside the cells, particularly in the brain and nervous system, leading to progressive damage. Over time, this accumulation disrupts normal neurological functions.
How is Lysosomal storage disease, CNP-related tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.