Cavitating leukodystrophy
Also known as: Kavitierende Leukodystrophie · Leukodystrophie mit Kavitation · Canine cavitating leukodystrophy · Leukodystrophy, cavitating
Overview
What it is
Cavitating leukodystrophy is an inherited neurological disorder affecting the brain and spinal cord. It occurs when the myelin sheath, which acts as the protective insulation around nerve fibers, degenerates and breaks down. This destruction leaves behind fluid-filled cavities in the brain tissue, disrupting the transmission of nerve signals.
How it presents
Symptoms typically appear during puppyhood and include coordination issues, tremors, and progressive weakness. These signs rapidly worsen over time, eventually leading to paralysis.
Treatment
This condition is currently incurable, and management is focused on palliative care or early euthanasia. Associated veterinary costs for diagnosis and supportive care generally range from 500 to 2500 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Cavitating leukodystrophy?
Cavitating leukodystrophy is an inherited neurological disorder affecting the brain and spinal cord. It occurs when the myelin sheath, which acts as the protective insulation around nerve fibers, degenerates and breaks down. This destruction leaves behind fluid-filled cavities in the brain tissue, disrupting the transmission of nerve signals.
How is Cavitating leukodystrophy tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.