Chronic monocytic leukemia(CMoL)
Also known as: Chronische monozytäre Leukämie · Canine chronic monocytic leukemia · Monozyten-Leukämie beim Hund
Overview
What it is
Chronic monocytic leukemia is a rare cancer of the blood and bone marrow where the body produces an uncontrolled excess of monocytes, which are a specific type of white blood cell. This overproduction is driven by acquired genetic mutations in the blood-forming cells, similar to some human leukemias. Over time, these abnormal cells crowd out healthy blood cells, which can impair normal oxygen delivery and immune function.
How it presents
This condition typically develops gradually in older dogs. Owners may notice progressive symptoms such as a loss of appetite, weight loss, low energy, pale gums, and swelling in the abdomen or lymph nodes.
Treatment
While the disease is not curable, it can be managed with lifelong supportive therapies, including chemotherapy and steroids, to temporarily stabilize the dog's quality of life. Treatment and monitoring typically cost between 3,000 and 10,000 EUR.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Chronic monocytic leukemia?
Chronic monocytic leukemia is a rare cancer of the blood and bone marrow where the body produces an uncontrolled excess of monocytes, which are a specific type of white blood cell. This overproduction is driven by acquired genetic mutations in the blood-forming cells, similar to some human leukemias. Over time, these abnormal cells crowd out healthy blood cells, which can impair normal oxygen delivery and immune function.
How is Chronic monocytic leukemia tested?
Various clinical and genetic tests are used depending on the breed and presentation.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.