Lethality, BTBD17-related
Also known as: BTBD17-related lethality · BTBD17 embryonic lethality · Lethaler Entwicklungsdefekt (BTBD17) · BTBD17-assoziierte Letalität · Abortion (embryonic lethality), BTBD17-related · …
Overview
What it is
This genetic condition is caused by a mutation in the BTBD17 gene, which disrupts normal embryonic development. It affects multiple vital organ systems during the early stages of growth, leading to a severe failure to develop properly. This disruption is so critical to life that the affected puppies cannot survive to term or past the first few days of life.
How it presents
Owners will typically only notice smaller litter sizes if the puppies pass away before birth. If born alive, affected puppies show extreme weakness and fail to survive past the first few days of life.
Treatment
There is no treatment available for this fatal condition. Because affected puppies do not survive, there are no ongoing medical management or treatment costs, resulting in an expected cost of 0 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Lethality, BTBD17-related?
This genetic condition is caused by a mutation in the BTBD17 gene, which disrupts normal embryonic development. It affects multiple vital organ systems during the early stages of growth, leading to a severe failure to develop properly. This disruption is so critical to life that the affected puppies cannot survive to term or past the first few days of life.
How is Lethality, BTBD17-related tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel, Feragen Komplettpaket (rassespezifisch).
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.