Dilated Cardiomyopathy, risk variant 2 (Dobermann)(DCM)
Also known as: Dilated Cardiomyopathy Variant 2 · Doberman DCM2 · DCM2 · Dilatative Kardiomyopathie Typ 2 · Dobermann-Kardiomyopathie · …
Overview
What it is
Dilated cardiomyopathy (DCM) is a severe genetic disease of the heart muscle where the heart's chambers become stretched, enlarged, and weakened. This stretching prevents the heart from contracting normally, making it difficult to pump blood effectively to the rest of the body. It is inherited in an autosomal-dominant pattern, meaning a dog only needs to inherit one copy of the risk variant to be susceptible, though not all dogs with the variant will develop the disease.
How it presents
Symptoms typically appear in middle-aged dogs and include rapid fatigue during exercise, coughing, shortness of breath, or sudden fainting. Because the disease often progresses silently, some dogs may not show any outward signs until they experience acute heart failure.
Treatment
While DCM is incurable and progressive, the disease can be managed with lifelong daily medications and regular veterinary heart checks. Lifetime management and diagnostic costs typically range from 3,000 to 10,000 EUR.
How it's tested
DCM DNA-Test (Dilatative Kardiomyopathie)(DCM)
Primary testDNA testDCM-assoziierte Mutation (z.B. PDK4 bei Dobermann). Mehrere Mutationen je nach Rasse.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Herzultraschall (Echokardiographie)(Herz-Echo)
Cardiac examEchokardiographie zur Beurteilung von Herzklappen, -wänden, -funktion. Pflicht z.B. bei Cavalier King Charles Spaniel (MMVD).
Issuing body: vet
Result scheme: Cardiac-OFA
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
DNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Dilated Cardiomyopathy, risk variant 2 (Dobermann)?
Dilated cardiomyopathy (DCM) is a severe genetic disease of the heart muscle where the heart's chambers become stretched, enlarged, and weakened. This stretching prevents the heart from contracting normally, making it difficult to pump blood effectively to the rest of the body. It is inherited in an autosomal-dominant pattern, meaning a dog only needs to inherit one copy of the risk variant to be susceptible, though not all dogs with the variant will develop the disease.
How is Dilated Cardiomyopathy, risk variant 2 (Dobermann) tested?
Tests currently in our database: DCM DNA-Test (Dilatative Kardiomyopathie), Herzultraschall (Echokardiographie), Labogen Komplettpaket (rassespezifisch), Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.