Juvenile Myoclonic Epilepsy (Rhodesian Ridgeback)(JME)
Also known as: Juvenile Myoclonic Epilepsy · Myoklonische Epilepsie des Rhodesian Ridgeback · DIRAS1-Epilepsie · Juvenile myoklonische Epilepsie · JME-Epilepsie · …
Overview
What it is
Juvenile Myoclonic Epilepsy (JME) is an inherited neurological disorder affecting the brain and nervous system. It is caused by a genetic mutation that leads to abnormal, uncontrolled electrical activity in the brain. This disruption in normal brain signaling results in sudden, involuntary muscle twitches, which are referred to as myoclonus.
How it presents
Owners will typically notice sudden, brief muscle jerks or twitches, especially when the dog is resting, relaxing, or falling asleep. These symptoms usually first appear in young dogs between the ages of 6 weeks and 18 months.
Treatment
While the condition is lifelong and cannot be cured, it can be managed with daily anti-epileptic medications and regular veterinary monitoring. Managing this chronic condition over the dog's lifetime typically costs between 2,000 and 7,000 EUR.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Juvenile Myoklonische Epilepsie (JME) DNA-Test(JME)
Primary testDNA testEin DNA-Test zum Nachweis der Mutation im DIRAS1-Gen, die für die juvenile myoklonische Epilepsie (JME) verantwortlich ist.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
1 of 1 breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Juvenile Myoclonic Epilepsy (Rhodesian Ridgeback)?
Juvenile Myoclonic Epilepsy (JME) is an inherited neurological disorder affecting the brain and nervous system. It is caused by a genetic mutation that leads to abnormal, uncontrolled electrical activity in the brain. This disruption in normal brain signaling results in sudden, involuntary muscle twitches, which are referred to as myoclonus.
How is Juvenile Myoclonic Epilepsy (Rhodesian Ridgeback) tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Juvenile Myoklonische Epilepsie (JME) DNA-Test, Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Rhodesian Ridgeback.