Ichthyosis, ABHD5-related(ICT-ABHD5)
Also known as: ABHD5-related ichthyosis · ABHD5-associated ichthyosis · Ichthyose (ABHD5-Typ) · Canine ABHD5 ichthyosis · ABHD5-congenital ichthyosis
Overview
What it is
This is an inherited skin disorder caused by a genetic mutation that disrupts how the skin metabolizes fats. Because the skin cannot properly build its outer protective barrier, it leads to abnormal scaling and dryness. This condition primarily affects the skin's outer layer, preventing it from retaining moisture and protecting against irritants.
How it presents
Owners will typically notice widespread, heavy skin scaling and a very dry coat starting in puppyhood. Affected dogs are also prone to developing secondary skin infections that cause itching and discomfort.
Treatment
While there is no cure, the condition can be managed lifelong using specialized topical shampoos, moisturizing rinses, and dietary supplements. Ongoing supportive care typically costs between 1,500 and 6,000 EUR.
How it's tested
Ichthyose (ABHD5-assoziiert) DNA-Test(ICT-ABHD5)
Primary testDNA testEin molekularbiologischer DNA-Test zum Nachweis der ursächlichen Mutation im ABHD5-Gen, die zu dieser Form der Ichthyose führt.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Ichthyosis, ABHD5-related?
This is an inherited skin disorder caused by a genetic mutation that disrupts how the skin metabolizes fats. Because the skin cannot properly build its outer protective barrier, it leads to abnormal scaling and dryness. This condition primarily affects the skin's outer layer, preventing it from retaining moisture and protecting against irritants.
How is Ichthyosis, ABHD5-related tested?
Tests currently in our database: Ichthyose (ABHD5-assoziiert) DNA-Test.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.