Hypoadrenocorticism (Addison's disease)(HA)
Also known as: Morbus Addison · Addison's Disease · Hypoadrenokortizismus · Nebennierenrindeninsuffizienz · Canine Hypoadrenocorticism · …
Overview
What it is
Addison's disease is a hormonal disorder where the outer layer of the adrenal glands, known as the adrenal cortex, fails to produce enough essential hormones like cortisol and aldosterone. Cortisol helps the dog's body manage stress and metabolism, while aldosterone regulates the balance of water and vital minerals. Without these hormones, the body cannot properly control its internal fluid levels or respond to daily physical stress.
How it presents
Symptoms typically appear in young to middle-aged dogs and often develop gradually, presenting as vomiting, diarrhea, weight loss, extreme lethargy, and tremors. In some cases, the condition can lead to a sudden, life-threatening collapse known as an Addisonian crisis.
Treatment
Although the condition is incurable and requires lifelong hormone replacement therapy and regular blood monitoring, it is highly manageable. Lifetime treatment and monitoring costs generally range from 3,000 to 12,000 EUR.
How it's tested
ACTH-Stimulationstest(ACTH-Stim)
Primary testClinical examDer ACTH-Stimulationstest ist der Goldstandard zur Diagnose von Morbus Addison. Er misst die Cortisolkonzentration im Blut vor und nach der Gabe von synthetischem ACTH.
Issuing body: vet
Result scheme: Clear/Carrier/Affected
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Hypoadrenocorticism (Addison's disease)?
Addison's disease is a hormonal disorder where the outer layer of the adrenal glands, known as the adrenal cortex, fails to produce enough essential hormones like cortisol and aldosterone. Cortisol helps the dog's body manage stress and metabolism, while aldosterone regulates the balance of water and vital minerals. Without these hormones, the body cannot properly control its internal fluid levels or respond to daily physical stress.
How is Hypoadrenocorticism (Addison's disease) tested?
Tests currently in our database: ACTH-Stimulationstest.
Which breeds are most affected?
Most commonly affected: Irish Soft Coated Wheaten Terrier, Nova Scotia Duck Tolling Retriever, West Highland White Terrier.